TY - JOUR TI - Adherence to Mediterranean Diet and Frailty AU - Ntanasi, E. AU - Yannakoulia, M. AU - Kosmidis, M.-H. AU - Anastasiou, C.A. AU - Dardiotis, E. AU - Hadjigeorgiou, G. AU - Sakka, P. AU - Scarmeas, N. JO - Journal of the American Medical Directors Association PY - 2018 VL - 19 TODO - 4 SP - 315-322.e2 PB - ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA SN - 1525-8610, 1538-9375 TODO - 10.1016/j.jamda.2017.11.005 TODO - aged; alcohol consumption; alcoholic beverage; Article; caloric intake; candy; cereal; dairy product; dementia; depression; female; fish; food frequency questionnaire; frailty; fruit; Greece; grip strength; human; legume; major clinical study; male; meat; Mediterranean diet; patient compliance; vegetable; very elderly; age; cross-sectional study; dementia; frail elderly; frailty; longitudinal study; Mediterranean diet; multivariate analysis; patient compliance; prevalence; risk assessment; sex factor; statistical model, Age Factors; Aged; Aged, 80 and over; Cross-Sectional Studies; Dementia; Diet, Mediterranean; Frail Elderly; Frailty; Greece; Humans; Logistic Models; Longitudinal Studies; Male; Multivariate Analysis; Patient Compliance; Prevalence; Risk Assessment; Sex Factors TODO - Objective: Το investigate associations between adherence to the Mediterranean diet and frailty in a Greek population of older adults. Design: Cross-sectional study. Setting: Data were drawn from the Hellenic longitudinal Investigation of Aging and Diet (HELIAD), a population-based, multidisciplinary study designed to estimate the prevalence and incidence of dementia in the Greek population. Participants: Data from 1740 participants aged ≥65 years were included in the present analysis. Participants were selected through random sampling from the records of 2 Greek municipalities. Measurements: Adherence to Mediterranean diet was evaluated through the MedDietScore, calculated from the information participants provided to a validated food frequency questionnaire. Frailty was assessed using 3 different definitions (the phenotypic approach proposed by Fried et al, the Frailty Index, and the Tilburg Frailty Indicator). Unadjusted and adjusted logistic and linear regression models were performed. Results: Of our participants, 70 (4%), 325 (18.7%), and 442 (25.4%) were identified as frail according to the Fried et al definition, the Frailty Index, and the Tilburg Frailty Indicator, respectively. Adjusting for confounding factors, each additional unit in the MedDietScore was associated with a 5% (P =.09), 4% (P =.005), and 7% (P <.001) decrease in the odds for frailty according to the Fried definition, the Frailty Index, and the Tilburg Frailty Indicator, respectively. Conclusions: According to study results, a higher adherence to the Mediterranean diet was associated with lower odds of frailty, irrespective of the definition used. This finding may be of relevance in the setting of population-based prevention efforts as well as in clinical practice. © 2017 AMDA – The Society for Post-Acute and Long-Term Care Medicine ER -