TY - JOUR TI - Mediterranean dietary patterns and prospective weight change in participants of the EPIC-PANACEA project AU - Romaguera, D. AU - Norat, T. AU - Vergnaud, A.-C. AU - Mouw, T. AU - May, A.M. AU - Agudo, A. AU - Buckland, G. AU - Slimani, N. AU - Rinaldi, S. AU - Couto, E. AU - Clavel-Chapelon, F. AU - Boutron-Ruault, M.-C. AU - Cottet, V. AU - Rohrmann, S. AU - Teucher, B. AU - Bergmann, M. AU - Boeing, H. AU - Tjønneland, A. AU - Halkjaer, J. AU - Jakobsen, M.U. AU - Dahm, C.C. AU - Travier, N. AU - Rodriguez, L. AU - Sanchez, M.J. AU - Amiano, P. AU - Barricarte, A. AU - Huerta, J.M. AU - Luan, J. AU - Wareham, N. AU - Key, T.J. AU - Spencer, E.A. AU - Orfanos, P. AU - Naska, A. AU - Trichopoulou, A. AU - Palli, D. AU - Agnoli, C. AU - Mattiello, A. AU - Tumino, R. AU - Vineis, P. AU - Bueno-de-Mesquita, H.B. AU - Büchner, F.L. AU - Manjer, J. AU - Wirfält, E. AU - Johansson, I. AU - Hellstrom, V. AU - Lund, E. AU - Braaten, T. AU - Engeset, D. AU - Odysseos, A. AU - Riboli, E. AU - Peeters, P.H.M. JO - AMERICAN JOURNAL OF CLINICAL NUTRITION PY - 2010 VL - 92 TODO - 4 SP - 912-921 PB - SN - 0002-9165 TODO - 10.3945/ajcn.2010.29482 TODO - adult; aged; article; body height; body weight; female; follow up; geographic distribution; human; male; Mediterranean diet; Mediterranean Diet Score; model; nutritional assessment; obesity; prospective study; scoring system; weight change; body mass; body weight; clinical trial; cohort analysis; educational status; Europe; middle aged; motor activity; multicenter study; obesity; patient compliance; probability; time, Adult; Body Mass Index; Body Weight; Cohort Studies; Diet, Mediterranean; Educational Status; Europe; Female; Humans; Male; Middle Aged; Motor Activity; Obesity; Overweight; Patient Compliance; Probability; Prospective Studies; Thinness; Time Factors TODO - Background: There is an association between a greater adherence to a Mediterranean diet and a reduced risk of developing chronic diseases. However, it is not clear whether this dietary pattern may be protective also against the development of obesity. Objective: We assessed the association between the adherence to the Mediterranean dietary pattern (MDP), prospective weight change, and the incidence of overweight or obesity. Design: We conducted a prospective cohort study [the European Prospective Investigation into Cancer and Nutrition-Physical Activity, Nutrition, Alcohol Consumption, Cessation of Smoking, Eating Out of Home, and Obesity (EPIC-PANACEA) project] in 373,803 individuals (103,455 men and 270,348 women; age range: 25-70 y) from 10 European countries. Anthropometric measurements were obtained at recruitment and after a median follow-up time of 5 y. The relative Mediterranean Diet Score (rMED; score range: 0-18) was used to assess adherence to the MDP according to the consumption of 9 dietary components that are characteristic of the Mediterranean diet. The association between the rMED and 5-y weight change was modeled through multiadjusted mixed-effects linear regression. Results: Individuals with a high adherence to the MDP according to the rMED (11-18 points) showed a 5-y weight change of -0.16 kg (95% CI: -0.24, -0.07 kg) and were 10% (95% CI: 4%, 18%) less likely to develop overweight or obesity than were individuals with a low adherence to the MDP (0-6 points). The low meat content of the Mediterranean diet seemed to account for most of its positive effect against weight gain. Conclusion: This study shows that promoting the MDP as a model of healthy eating may help to prevent weight gain and the development of obesity. © 2010 American Society for Nutrition. ER -