TY - JOUR TI - Specific food group combinations explaining the variation in intakes of nutrients and other important food components in the european prospective investigation into cancer and nutrition: An application of the reduced rank regression method AU - Kröger, J. AU - Ferrari, P. AU - Jenab, M. AU - Bamia, C. AU - Touvier, M. AU - Bueno-De-Mesquita, H.B. AU - Fahey, M.T. AU - Benetou, V. AU - Schulz, M. AU - Wirfält, E. AU - Boeing, H. AU - Hoffmann, K. AU - Schulze, M.B. AU - Orfanos, P. AU - Oikonomou, E. AU - Huybrechts, I. AU - Rohrmann, S. AU - Pischon, T. AU - Manjer, J. AU - Agren, A. AU - Navarro, C. AU - Jakszyn, P. AU - Boutron-Ruault, M.C. AU - Niravong, M. AU - Khaw, K.T. AU - Crowe, F. AU - Ocké, M.C. AU - Van Der Schouw, Y.T. AU - Mattiello, A. AU - Bellegotti, M. AU - Engeset, D. AU - Hjartåker, A. AU - Egeberg, R. AU - Overvad, K. AU - Riboli, E. AU - Bingham, S. AU - Slimani, N. JO - European Journal of Clinical Nutrition PY - 2009 VL - 63 TODO - null SP - S263-S274 PB - SN - 0954-3007, 1476-5640 TODO - 10.1038/ejcn.2009.85 TODO - alcohol; alpha tocopherol; ascorbic acid; beta carotene; calcium; cholesterol; cyanocobalamin; disaccharide; iron; magnesium; margarine; monosaccharide; monounsaturated fatty acid; phosphorus; polyunsaturated fatty acid; potassium; pyridoxine; retinol; riboflavin; saturated fatty acid; starch; thiamine; vegetable oil; vitamin D, adult; aged; alcohol consumption; article; bread; calcium intake; carbohydrate intake; cheese; cholesterol intake; controlled study; dietary fiber; Europe; fat intake; female; food composition; food intake; human; iron intake; male; milk; mineral intake; normal human; phosphate intake; potassium intake; potato; prospective study; protein intake; red meat; regression analysis; vitamin intake, Adult; Aged; Data Interpretation, Statistical; Diet; Diet Records; Diet Surveys; Energy Intake; Europe; Female; Humans; Male; Middle Aged; Prospective Studies; Regression Analysis, Solanum tuberosum TODO - Objective:To identify combinations of food groups that explain as much variation in absolute intakes of 23 key nutrients and food components as possible within the country-specific populations of the European Prospective Investigation into Cancer and Nutrition (EPIC).Subjects/Methods:The analysis covered single 24-h dietary recalls (24-HDR) from 36 034 subjects (13 025 men and 23 009 women), aged 35–74 years, from all 10 countries participating in the EPIC study. In a set of 39 food groups, reduced rank regression (RRR) was used to identify those combinations (RRR factors) that explain the largest proportion of variation in intake of 23 key nutrients and food components, namely, proteins, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, cholesterol, sugars (sum of mono- and disaccharides), starch, fibre, alcohol, calcium, iron, potassium, phosphorus, magnesium, vitamin D, β-carotene, retinol and vitamins E, B1, B2, B6, B12 and C (RRR responses). Analyses were performed at the country level and for all countries combined. Results: In the country-specific analyses, the first RRR factor explained a considerable proportion of the total nutrient intake variation in all 10 countries (27.4–37.1%). The subsequent RRR factors were much less important in explaining the variation (⩽6%). Strong similarities were observed for the first country-specific RRR factor between the individual countries, largely characterized by consumption of bread, vegetable oils, red meat, milk, cheese, potatoes, margarine and processed meat. The highest explained variation was seen for protein, potassium, phosphorus and magnesium (50–70%), whereas sugars, β-carotene, retinol and alcohol were only marginally explained (⩽5%). The explained proportion of the other nutrients ranged between these extremes.Conclusions:A combination of food groups was identified that explained a considerable proportion of the nutrient intake variation in 24-HDRs in every country-specific EPIC population in a similar manner. This indicates that, despite the large variability in food and nutrient intakes reported in the EPIC, the variance of intake of important nutrients is explained, to a large extent, by similar food group combinations across countries. © 2009 Macmillan Publishers Limited. All rights reserved. ER -