TY - JOUR TI - The autoimmunity–oral microbiome connection AU - Nikitakis, N.G. AU - Papaioannou, W. AU - Sakkas, L.I. AU - Kousvelari, E. JO - Journal of Oral Diseases PY - 2017 VL - 23 TODO - 7 SP - 828-839 PB - Wiley-Blackwell Publishing Ltd SN - 2314-6516 TODO - 10.1111/odi.12589 TODO - citrulline, arthritis; autoimmune disease; autoimmunity; Crohn disease; human; immunopathogenesis; mouth flora; nonhuman; priority journal; Review; rheumatoid arthritis; Sjoegren syndrome; species composition; systemic lupus erythematosus; virus infection; autoimmunity; Crohn disease; dysbiosis; immunology; intestine flora; microbiology; mouth; rheumatoid arthritis; Sjoegren syndrome; systemic lupus erythematosus, Arthritis, Rheumatoid; Autoimmunity; Crohn Disease; Dysbiosis; Gastrointestinal Microbiome; Humans; Lupus Erythematosus, Systemic; Mouth; Sjogren's Syndrome TODO - To date, there is a major effort in deciphering the role of complex microbial communities, especially the oral and gut microbiomes, in the pathogenesis of various diseases. Increasing evidence indicates a key role for the oral microbiome in autoimmune diseases. In this review article, we discuss links of the oral microbiota to a group of autoimmune diseases, that is, Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), Crohn's disease (CD), and rheumatoid arthritis (RA). We particularly focus on factors that affect the balance between the immune system and the composition of microbiota leading to dysbiosis, loss of tolerance and subsequent autoimmune disease progression and maintenance. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd ER -