TY - JOUR TI - The use of platelet-rich plasma combined with demineralized freeze-dried bone allograft in the treatment of periodontal endosseous defects: A report of two clinical cases AU - Markou, N. AU - Pepelassi, E. AU - Kotsovilis, S. AU - Vrotsos, I. AU - Vavouraki, H. AU - Stamatakis, H.C. JO - JADA. THE JOURNAL OF THE AMERICAN DENTAL ASSOCIATION PY - 2010 VL - 141 TODO - 8 SP - 967-978 PB - American Dental Association SN - 0002-8177 TODO - 10.14219/jada.archive.2010.0310 TODO - null TODO - Background. On the basis of systematic reviews and randomized controlled trials, the authors provide reports of two cases in which platelet-rich plasma (PRP) combined with demineralized freeze-dried bone allograft (DFDBA) was used to treat periodontal endosseous defects. Case Pescriptions. Clinicians treated two circumferential endosseous defects with a probing pocket depth of 5 and 8 millimeters, respectively (case 1), and a combined 1-2-3-wall endosseous defect with a probing pocket depth of 6 mm (case 2) by using the combination of PRP and DFDBA. At six months, complete periodontal pocket resolution occurred in all defects, and clinical attachment level and radiographic defect fill in all defects exhibited significant improvement compared with presurgical values. Clinical Implications. The combination of PRP and DFDBA may be clinically and radiographically efficacious in the treatment of periodontal endosseous defects. ER -