TY - JOUR
TI - HLA-B27 frequency in Greek patients with acute anterior uveitis
AU - Zervas, J.
AU - Tsokos, G.
AU - Papadakis, G.
AU - Kabouklis, E.
AU - Papadopoulos, D.
JO - British Journal of Ophthalmology
PY - 1977
VL - 61
TODO - 11
SP - 699-701
PB - BMJ Publishing Group
SN - 0007-1161, 1468-2079
TODO - 10.1136/bjo.61.11.699
TODO - HLA antigen, acute disease;  adult;  article;  comparative study;  female;  genetics;  Greece;  human;  immunology;  iridocyclitis;  male;  Reiter syndrome;  rheumatoid arthritis;  sex difference, Acute Disease;  Adult;  Arthritis, Rheumatoid;  Comparative Study;  Female;  Greece;  HLA Antigens;  Human;  Male;  Middle Age;  Reiter Disease;  Sex Factors;  Uveitis, Anterior
TODO - The histocompatibility antigen HLA-B27 was identified in 12 out of 33 patients with acute non-granulomatous anterior uveitis. This is a frequency of 36·36%, compared with 4·72% in controls. Seven patients had in addition evidence of systemic disease, including ankylosing spondylitis, sacroiliitis, Reiter's disease, Still's disease, and rheumatoid arthritis. Five of these were HLA-B27 positive, which suggests that the uveitis in many of these cases has a similar aetiology to the uveitis in those with rheumatic disease. It appears that the more severe cases of acute anterior uveitis are related more frequently to the presence of HLA-B27.
ER -