TY - JOUR
TI - Temporal trends in stroke incidence and case-fatality rates in Arcadia, Greece: A sequential, prospective, population-based study
AU - Karantali, E.
AU - Vemmos, K.
AU - Tsampalas, E.
AU - Xynos, K.
AU - Karachalia, P.
AU - Lambrou, D.
AU - Angeloglou, S.
AU - Kazakou, M.
AU - Karagianni, A.
AU - Aravantinou-Fatorou, K.
AU - Karakatsani, E.
AU - Bots, M.L.
AU - Karamatzianni, G.
AU - Bellos, S.
AU - Ntiloudis, R.
AU - Lypiridou, M.
AU - Gamvoula, A.
AU - Georgiopoulos, G.
AU - Ajdini, E.
AU - Gatselis, N.
AU - Makaritsis, K.
AU - Korompoki, E.
AU - Ntaios, G.
JO - International Journal of Stroke
PY - 2022
VL - 17
TODO - 1
SP - 37-47
PB - SAGE Publications Inc.
SN - 1747-4930, 1747-4949
TODO - 10.1177/1747493021995594
TODO - adult;  aged;  Article;  case fatality rate;  cerebrovascular accident;  female;  Greece;  human;  incidence;  major clinical study;  male;  mortality rate;  population research;  prospective study;  risk assessment;  risk factor;  sex difference;  trend study;  cerebrovascular accident;  income;  register, Greece;  Humans;  Incidence;  Income;  Prospective Studies;  Registries;  Stroke
TODO - Background: Stroke incidence and case-fatality are reported to decline in high-income countries during the last decades. Epidemiological studies are important for health services to organize prevention and treatment strategies. Aims: The aim of this population-based study was to determine temporal trends of stroke incidence and case-fatality rates of first-ever stroke in Arcadia, a prefecture in southern Greece. Methods: All first-ever stroke cases in the Arcadia prefecture were ascertained using the same standard criteria and multiple overlapping sources in three study periods: from November 1993 to October 1995; 2004; and 2015–2016. Crude and age-adjusted to European population incidence rates were compared using Poisson regression. Twenty-eight days case fatality rates were estimated and compared using the same method. Results: In total, 1315 patients with first-ever stroke were identified. The age-standardized incidence to the European population was 252 per 100,000 person-years (95% CI 231–239) in 1993/1995, 252 (95% CI 223–286) in 2004, and 211 (192–232) in 2015/2016. The overall age- and sex-adjusted incidence rates fell by 16% (incidence rates ratio 0.84, 95% CI: 0.72–0.97). Similarly, 28-day case-fatality rate decreased by 28% (case fatality rate ratio = 0.72, 95% CI: 0.58–0.90). Conclusions: This population-based study reports a significant decline in stroke incidence and mortality rates in southern Greece between 1993 and 2016. © 2021 World Stroke Organization.
ER -