TY - JOUR
TI - Jitter Remains Stable throughout a Single Fiber EMG Session in Healthy and Myasthenic Muscles
AU - Anagnostou, E.
AU - Dimopoulou, P.
AU - Zouvelou, V.
AU - Karandreas, N.
AU - Zambelis, T.
JO - Journal of Neuromuscular Diseases
PY - 2021
VL - 8
TODO - 2
SP - 295-298
PB - IOS Press BV
SN - 2214-3599, 2214-3602
TODO - 10.3233/JND-200599
TODO - cholinergic receptor;  cholinesterase inhibitor;  immunosuppressive agent;  protein muscle specific receptor tyrosine kinase antibody;  protein tyrosine kinase;  pyridostigmine;  steroid;  unclassified drug, aging;  Article;  comparative study;  diagnostic accuracy;  electromyography;  fatigue;  human;  informed consent;  innervation;  motor unit;  muscle contraction;  myasthenia gravis;  neuromuscular junction;  neurophysiology;  orbicularis oculi muscle;  priority journal;  sensitivity and specificity;  single fiber electromyography;  treatment withdrawal;  adolescent;  adult;  aged;  case control study;  electromyography;  female;  male;  middle aged;  muscle fatigue;  myasthenia gravis;  pathophysiology;  procedures;  very elderly;  young adult, Adolescent;  Adult;  Aged;  Aged, 80 and over;  Case-Control Studies;  Electromyography;  Female;  Humans;  Male;  Middle Aged;  Muscle Fatigue;  Myasthenia Gravis;  Young Adult
TODO - Fatigability is the hallmark of myasthenia gravis (MG). It is not clear, however, whether there is an analogous increase in jitter during the course of a single fiber electromyography (SFEMG) session. The individual jitter values of all potentials of 76 normal and 44 myasthenic orbicularis oculi muscles were assigned a rank number according to their temporal order in which they were collected and linear regression was performed to determine if the slope of the regression line was significantly different from zero. Control and MG subjects displayed rather flat linear regression lines with non-significant positive or negative slopes. Accordingly, ROC analysis yielded areas under the curve near 0.5. We conclude that there is no systematic jitter increase during the collection of 20 potential pairs in a typical SFEMG session. © 2021 - IOS Press. All rights reserved.
ER -