TY - JOUR
TI - The Role of Disorganization of Retinal Inner Layers as Predictive Factor of Postoperative Outcome in Patients with Epiretinal Membrane
AU - Garnavou-Xirou, C.
AU - Xirou, T.
AU - Gkizis, I.
AU - Kabanarou, S.A.
AU - Dimitriou, E.
AU - Theodossiadis, P.
AU - Chatziralli, I.
JO - Ophthalmic Research
PY - 2020
VL - 63
TODO - 1
SP - 13-17
PB - S Karger AG
SN - 0030-3747, 1423-0259
TODO - 10.1159/000499370
TODO - aged;  Article;  best corrected visual acuity;  central retinal thickness;  clinical article;  correlation analysis;  epiretinal membrane;  external limiting membrane;  female;  human;  male;  pars plana vitrectomy;  postoperative period;  prediction;  preoperative evaluation;  priority journal;  prognosis;  retina fovea;  retinal inner nuclear layer;  retinal inner plexiform layer;  retrospective study;  spectral domain optical coherence tomography;  treatment outcome;  fluorescence angiography;  middle aged;  optical coherence tomography;  pathology;  predictive value;  retina;  very elderly;  vitrectomy, Aged;  Aged, 80 and over;  Epiretinal Membrane;  Female;  Fluorescein Angiography;  Humans;  Male;  Middle Aged;  Predictive Value of Tests;  Retina;  Retrospective Studies;  Tomography, Optical Coherence;  Vitrectomy
TODO - Purpose: The purpose of this retrospective study was to evaluate the disorganization of the retinal inner layers (DRIL) as a potential predictive factor of postoperative visual outcome in patients with idiopathic epiretinal membrane (iERM), treated with pars plana vitrectomy (PPV). Methods: Participants in the study were 46 consecutive patients diagnosed with iERM, who underwent PPV. Best corrected visual acuity (BCVA) measurement and spectral-domain optical coherence tomography (SD-OCT) were performed at baseline (preoperatively), and at months 3 and 6 postoperatively. DRIL and additional OCT parameters were assessed at 1-mm-wide foveal centered area. Results: DRIL was observed in 47.8% of patients at baseline. There was statistically significant improvement in BCVA and central retinal thickness (CRT) between baseline and months 6 and 12 in all patients. There was a statistically significant difference in BCVA and CRT change between patients with and without DRIL at months 6 and 12 compared to baseline, showing that there was a correlation between change in BCVA or CRT and baseline DRIL. Ellipsoid zone and external limiting membrane were intact in 91.3 and 95.7%, respectively, not affecting our results. Conclusions: Baseline DRIL has been shown to be predictive of postoperative visual outcome in patients with iERM, treated with PPV. © 2019 © 2019 S. Karger AG, Basel.
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