TY - JOUR TI - End-stage dementia spark of life: Reliability and validity of the “GATOS” questionnaire AU - Tsoucalas, G. AU - Bourelia, S. AU - Kalogirou, V. AU - Giatsiou, S. AU - Mavrogiannaki, E. AU - Gatos, G. AU - Galanos, A. AU - Repana, O. AU - Iliadou, E. AU - Antoniou, A. AU - Sgantzos, M. AU - Gatos, K. JO - Current Alzheimer Research PY - 2015 VL - 12 TODO - 2 SP - 179-188 PB - Bentham Science Publishers B.V. SN - 1567-2050 TODO - 10.2174/1567205012666150204122635 TODO - Article; criterion related validity; dementia; discriminant validity; female; human; interrater reliability; major clinical study; male; Mini Mental State Examination; prevalence; priority journal; quality of life; questionnaire; reliability; test retest reliability; validity; age; aged; dementia; educational status; employment; mental health; middle aged; procedures; reproducibility; rural population; terminal care; urban population; validation study; very elderly, Age Factors; Aged; Aged, 80 and over; Dementia; Educational Status; Employment; Female; Humans; Male; Mental Status Schedule; Middle Aged; Quality of Life; Reproducibility of Results; Rural Population; Surveys and Questionnaires; Terminal Care; Urban Population TODO - Background: Floor effects are present in most dementia assessment tools as dementia progresses and the in–depth assessment of patients considered more or less on vegetative state is questionable. Objective: To develop a questionnaire (the “Gatos Clinical Test-GCT”) for the assessment of end-stage demented patients. Methods: Five hundred patients with dementia of various causes and an MMSE score between 0 and 2 were enrolled in the study. The GCT consists of 14 closed type questions rated on a Likert scale. The total score is used to evaluate patient’s dementia. Various aspects of validity and reliability (including face, content and structural validity as well as test-retest reliability) were examined. Results: Three subscales “Autonomy/Alertness”, “Gnosias” and “Somatokinetic function” were defined, with a Cronbach equal to 0.851, 0.756 and 0.598 respectively. The GCT subscales and total score were statistically significant higher in patients with MMSE score 1 or 2 compared with those with MMSE score 0 (p<0.0005). Patients with GCT total score less than 12.5 had 75% probability to have zero MMSE score. Conclusion: The “GATOS” questionnaire is a valid and reliable test for patients with severe dementia, aiming at identification of those patients who could sustain some quality of life. It is a relatively short and easy to administer tool. As dementia prevalence is expected to rise further worldwide we believe that GCT could offer valuable services to health professionals, caregivers and patients. © 2015 Bentham Science Publishers. ER -