TY - JOUR
TI - West Nile virus in humans, Greece, 2018: The largest seasonal number of cases, 9years after its emergence in the country
AU - Pervanidou, D.
AU - Vakali, A.
AU - Georgakopoulou, T.
AU - Panagiotopoulos, T.
AU - Patsoula, E.
AU - Koliopoulos, G.
AU - Politis, C.
AU - Stamoulis, K.
AU - Gavana, E.
AU - Pappa, S.
AU - Mavrouli, M.
AU - Emmanouil, M.
AU - Sourvinos, G.
AU - Mentis, A.
AU - Tsakris, A.
AU - Hadjichristodoulou, C.
AU - Tsiodras, S.
AU - Papa, A.
JO - Eurosurveillance
PY - 2020
VL - 25
TODO - 32
SP - null
PB - European Centre for Disease Prevention and Control (ECDC)
SN - 1025-496X, 1560-7917
TODO - 10.2807/1560-7917.ES.2020.25.32.1900543
TODO - adult;  aged;  Article;  blood donor;  blood safety;  epidemic;  female;  Flavivirus infection;  follow up;  geographic distribution;  Greece;  health education;  hospital discharge;  hospitalization;  human;  incidence;  interview;  laboratory diagnosis;  major clinical study;  male;  mosquito control;  public health service;  rural area;  urban area;  very elderly;  virus transmission;  West Nile virus;  West Nile virus infection;  animal;  blood;  epidemic;  health survey;  immunology;  isolation and purification;  procedures;  season;  West Nile fever;  West Nile virus;  young adult, virus antibody, Animals;  Antibodies, Viral;  Blood Donors;  Disease Outbreaks;  Female;  Greece;  Humans;  Population Surveillance;  Seasons;  West Nile Fever;  West Nile virus;  Young Adult
TODO - Background: Human cases of West Nile virus (WNV) infection are recorded since 2010 in Greece, with seasonal outbreaks occurring almost annually. Enhanced surveillance has been implemented since 2010, to promptly characterise cases’ temporal and geographical distribution and inform authorities for implementation of appropriate measures (mosquito control, health education, blood safety). Aim: We describe the epidemiology of WNV human infections in Greece focusing on the 2018 season. Methods: The National Public Health Organization advised physicians to test all suspect WNV infection cases and refer samples to reference laboratories. Laboratories notified diagnosed cases on a daily basis. Treating physicians, patients, and infected blood donors were interviewed within 48hours after diagnosis and the probable infection location was identified. Hospitalised cases were followed up until discharge. Results: A total of 317 autochthonous WNV infection cases were diagnosed in 2018. Among them, 243 cases had neuroinvasive disease (WNND), representing a 23% increase of WNND cases compared with 2010, the previous most intense season. There were 51 deaths. Cases started occurring from week22, earlier than usual. Both rural and urban areas were affected, with 86 (26% of the total) municipalities belonging to seven (54% of the total) regions recording cases. Two major epicentres were identified in Attica and Central Macedonia regions. Conclusions: The largest number of human cases of WNV infection ever recorded in Greece occurred in 2018, with a wide geographical distribution, suggesting intense virus circulation. Enhanced surveillance is vital for the early detection of human cases and the prompt implementation of response measures. © 2020 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
ER -