TY - JOUR
TI - Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study
AU - Menditto, E.
AU - Costa, E.
AU - Midão, L.
AU - Bosnic-Anticevich, S.
AU - Novellino, E.
AU - Bialek, S.
AU - Briedis, V.
AU - Mair, A.
AU - Rajabian-Soderlund, R.
AU - Arnavielhe, S.
AU - Bedbrook, A.
AU - Czarlewski, W.
AU - Annesi-Maesano, I.
AU - Anto, J.M.
AU - Devillier, P.
AU - De Vries, G.
AU - Keil, T.
AU - Sheikh, A.
AU - Orlando, V.
AU - Larenas-Linnemann, D.
AU - Cecchi, L.
AU - De Feo, G.
AU - Illario, M.
AU - Stellato, C.
AU - Fonseca, J.
AU - Malva, J.
AU - Morais-Almeida, M.
AU - Pereira, A.M.
AU - Todo-Bom, A.M.
AU - Kvedariene, V.
AU - Valiulis, A.
AU - Bergmann, K.C.
AU - Klimek, L.
AU - Mösges, R.
AU - Pfaar, O.
AU - Zuberbier, T.
AU - Cardona, V.
AU - Mullol, J.
AU - Papadopoulos, N.G.
AU - Prokopakis, E.P.
AU - Bewick, M.
AU - Ryan, D.
AU - Roller-Wirnsberger, R.E.
AU - Tomazic, P.V.
AU - Cruz, A.A.
AU - Kuna, P.
AU - Samolinski, B.
AU - Fokkens, W.J.
AU - Reitsma, S.
AU - Bosse, I.
AU - Fontaine, J.-F.
AU - Laune, D.
AU - Haahtela, T.
AU - Toppila-Salmi, S.
AU - Bachert, C.
AU - Hellings, P.W.
AU - Melén, E.
AU - Wickman, M.
AU - Bindslev-Jensen, C.
AU - Eller, E.
AU - O'Hehir, R.E.
AU - Cingi, C.
AU - Gemicioğlu, B.
AU - Kalayci, O.
AU - Ivancevich, J.C.
AU - Bousquet, J.
AU - the MASK group
JO - Clinical and Experimental Allergy
PY - 2019
VL - null
TODO - null
SP - null
PB - Wiley-Blackwell Publishing Ltd
SN - null
TODO - 10.1111/cea.13333
TODO - adult;  aged;  allergic rhinitis;  cell phone use;  clinical trial;  cross-sectional study;  female;  human;  male;  medical record;  medication compliance;  middle aged;  mobile application;  multicenter study;  outcome assessment;  questionnaire, Adult;  Aged;  Cell Phone Use;  Cross-Sectional Studies;  Female;  Humans;  Male;  Medical Records;  Medication Adherence;  Middle Aged;  Mobile Applications;  Patient Outcome Assessment;  Rhinitis, Allergic;  Surveys and Questionnaires
TODO - Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12 143 users were registered. A total of 6 949 users reported at least one VAS data recording. Among them, 1 887 users reported ≥7 VAS data. About 1 195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR ≥70% and PDC ≤1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting. © 2018 John Wiley & Sons Ltd
ER -