TY - JOUR
TI - Seroprevalence of hepatitis E in HIV infected patients in Greece
AU - Politou, M.
AU - Boti, S.
AU - Androutsakos, T.
AU - Valsami, S.
AU - Pittaras, T.
AU - Kapsimali, V.
JO - Journal of Medical Virology
PY - 2015
VL - 87
TODO - 9
SP - 1517-1520
PB - John Wiley and Sons Inc
SN - 0146-6615, 1096-9071
TODO - 10.1002/jmv.24214
TODO - hepatitis B surface antigen;  hepatitis C antibody;  immunoglobulin G;  hepatitis antibody;  hepatitis B surface antigen;  hepatitis C antibody, adult;  age;  aged;  antiviral therapy;  Article;  CD4 lymphocyte count;  controlled study;  correlational study;  disease association;  disease duration;  female;  Greece;  hepatitis A;  hepatitis E;  human;  Human immunodeficiency virus infection;  major clinical study;  male;  prospective study;  risk factor;  seroprevalence;  sexual orientation;  treatment duration;  virus load;  blood;  blood donor;  complication;  hepatitis E;  Hepatitis E virus;  HIV Infections;  immunology;  middle aged;  sexual behavior;  very elderly;  virology;  young adult, Hepatitis C virus, Adult;  Age Factors;  Aged;  Aged, 80 and over;  Blood Donors;  Female;  Greece;  Hepatitis Antibodies;  Hepatitis B Surface Antigens;  Hepatitis C Antibodies;  Hepatitis E;  Hepatitis E virus;  HIV Infections;  Humans;  Male;  Middle Aged;  Seroepidemiologic Studies;  Sexual Behavior;  Young Adult
TODO - HEV infection is an emerging public health problem worldwide Data concerning HEV infection in HIV+ patients in Greece is scare. The aim of the study was to determine HEV seroprevalence in patients with HIV infection in Greece. We studied 243 HIV(+) patients 214 men (88%) and 29 women (12%) with a median age of 45 years (range 19-83) who attended the HIV unit of Pathophysiology Department of Laikon General Hospital in Athens for the presence of anti-HEV IgG antibodies with (EIA) (EIA HEV IgG, Adaltis, Rome, Italy Eighteen/243 patients (7.3%) were positive for HEV IgG antibodies, a seroprevalence that was not different from that described for the blood donors group from Greece There was no difference of the presence of HbsAg, hepatitis C and hepatitis A between the HEV(+) and HEV(-) patients. There was no statistically significant difference between the HEV(+) and HEV(-) group in terms of HIV acquisition, sexual orientation, median duration of HIV infection, ART treatment, or duration of ART. Only the median age of HEV(+) was 52years (35-78) while that of HEV(-) was 44years (19-83)(P=0.03). Only 2/18(11.1%) HEV(+) HIV(+) patients had abnormal ALT and AST values. The seroprevalence of hepatitis E in HIV(+) patients in Greece seems to be the same with that of the general population thus implying that HIV infection is not a risk factor for HEV infection and only age shows a positive correlation with seropositivity. © 2015 Wiley Periodicals, Inc.
ER -