TY - JOUR
TI - Splenic granulomatous lesions in immunocompetent pediatric patients with visceral leishmaniasis
AU - Fretzayas, A.
AU - Moustaki, M.
AU - Kitsiou, S.
AU - Mathioudakis, J.
AU - Karpathios, T.
JO - Scandinavian Journal of Infectious Diseases
PY - 2001
VL - 33
TODO - 11
SP - 865-867
PB - 
SN - 0036-5548, 1651-1980
TODO - 10.1080/00365540110027141
TODO - amphotericin B lipid complex;  antileishmanial agent;  ceftazidime;  meglumine antimonate, article;  case report;  child;  clinical feature;  drug response;  echography;  granulomatosis;  hepatomegaly;  human;  immunocompetence;  intestine injury;  male;  prognosis;  spleen injury;  splenomegaly;  treatment outcome;  visceral leishmaniasis, Antiprotozoal Agents;  Child;  Child, Preschool;  Granuloma;  Humans;  Immunocompetence;  Infant;  Leishmaniasis, Visceral;  Male;  Meglumine;  Organometallic Compounds;  Prognosis;  Splenic Diseases;  Treatment Outcome
TODO - Visceral focal lesions are rarely encountered in patients with leishmaniasis despite the fact that splenomegaly, and to a lesser extent hepatomegaly, predominate among the clinical features of the disease. We present, using high resolution ultrasonography, the first 3 reported cases of focal splenic involvement in immunocompetent children with visceral leishmaniasis. All patients showed a prompt response to the conventional anti-leishmanial treatment administered. This favorable outcome indicates that localized splenic lesions should not be considered as a poor prognostic factor and that alteration of the standard anti-leishmanial regimens is not justified.
ER -