TY - JOUR
TI - Circulating resistin is a significant predictor of mortality independently from cardiovascular comorbidities in elderly, non-diabetic subjects with chronic kidney disease
AU - Marouga, A.
AU - Dalamaga, M.
AU - Kastania, A.N.
AU - Kroupis, C.
AU - Lagiou, M.
AU - Saounatsou, K.
AU - Dimas, K.
AU - Vlahakos, D.V.
JO - Biomarker Insights
PY - 2016
VL - 21
TODO - 1
SP - 73-79
PB - Taylor and Francis Ltd.
SN - 1177-2719
TODO - 10.3109/1354750X.2015.1118536
TODO - adiponectin;  C reactive protein;  cystatin C;  leptin;  n(g),n(g) dimethylarginine;  nicotinamide phosphoribosyltransferase;  oxidized low density lipoprotein;  resistin;  thyrotropin;  tumor necrosis factor alpha;  biological marker;  resistin;  RETN protein, human, aged;  Article;  atherosclerosis;  blood cell count;  blood sampling;  body mass;  cardiac patient;  cardiovascular mortality;  chronic kidney disease;  comorbidity;  comparative study;  diabetic patient;  disease association;  disease course;  enzyme linked immunosorbent assay;  female;  follow up;  geriatric patient;  glomerulus filtration rate;  heart rate;  high performance liquid chromatography;  homeostasis;  human;  laboratory test;  major clinical study;  male;  prediction;  smoking habit;  survival rate;  survivor;  systolic blood pressure;  thorax radiography;  urinalysis;  very elderly;  blood;  cardiovascular disease;  chronic kidney failure;  comorbidity;  Kaplan Meier method;  middle aged;  mortality;  prognosis;  receiver operating characteristic, Aged;  Biomarkers;  Cardiovascular Diseases;  Comorbidity;  Female;  Humans;  Kaplan-Meier Estimate;  Kidney Failure, Chronic;  Male;  Middle Aged;  Prognosis;  Resistin;  ROC Curve
TODO - Context: Resistin is associated with inflammation, atherosclerosis and cardiovascular (CV) disease.Objective: To associate circulating resistin with all-cause and CV mortality in chronic kidney disease (CKD) patients.Methods: Serum resistin was determined in a cohort of 80 elderly, non-diabetic patients with stable CKD at different stages in a follow-up period of 5 years.Results: Circulating resistin was significantly elevated in deceased compared to alive patients. Resistin emerged as an independent biomarker of all-cause and CV mortality after a 5-year follow-up period.Conclusion: Elevated circulating resistin was a significant independent predictor of CV and all-cause mortality in elderly, non-diabetic CKD patients. © 2015 Taylor & Francis.
ER -