TY - JOUR
TI - The chemical profile of pyrrolizidine alkaloids from selected greek endemic boraginaceae plants determined by gas chromatography/mass spectrometry
AU - Damianakos, H.
AU - Jeziorek, M.
AU - Pietrosiuk, A.
AU - Chinou, I.
JO - JOURNAL OF AOAC. INTERNATIONAL
PY - 2014
VL - 97
TODO - 5
SP - 1244-1249
PB - AOAC International
SN - 1060-3271
TODO - 10.5740/jaoacint.SGEDamianakos
TODO - Alkaloids;  Antennas;  Chromatographic analysis;  Gas plants;  Mass spectrometry;  Metabolites, Aerial parts;  Chemical profiles;  Gas chromatography/Mass spectrometry;  Literature data;  Mass spectra;  Pyrrolizidine alkaloid;  Qualitative test;  Retention index, Gas chromatography, plant extract;  pyrrolizidine alkaloid, Boraginaceae;  chemistry;  Greece;  isolation and purification;  mass fragmentography;  procedures, Boraginaceae;  Gas Chromatography-Mass Spectrometry;  Greece;  Plant Extracts;  Pyrrolizidine Alkaloids
TODO - Four Greek endemic Boraginaceae plants, Onosma erecta Sibth. & Sm., Onosma kaheirei Teppner, Onosma leptantha Heldr., and Cynoglossum columnae L. (aerial parts), were screened for their content of pyrrolizidine alkaloids (PAs). TLC with the Mattocks-Molyneux visualization reagent was used as a preliminary qualitative test for PA or PA N-oxide detection. The extracts of the species found to contain PAs and their N-oxides were further analyzed by GC/MS, so as to identify their structures by means of the mass spectra and retention index values of known PAs already published in the literature. Twenty-three PAs were identified. For additional peaks, recognized as possible PAs by their MS pattern, no exact structures were tentatively suggested, as a result of lack of matching literature data. Furthermore, a quantitative PA profile of the species was obtained.
ER -