TY - JOUR
TI - Pyrrolizidine alkaloids from Cynoglossum columnae Ten. (Boraginaceae)
AU - Damianakos, H.
AU - Jeziorek, M.
AU - Sykłowska-Baranek, K.
AU - Buchwald, W.
AU - Pietrosiuk, A.
AU - Chinou, I.
JO - Phytochemistry Letters
PY - 2016
VL - 15
TODO - null
SP - 234-237
PB - Elsevier Ireland Ltd
SN - 1874-3900
TODO - 10.1016/j.phytol.2016.02.005
TODO - 2' epi heliosupine n oxide;  3' o acetylrinderine n oxide;  9'' methyl lithospermate;  beta arbutin;  drug metabolite;  echinatine n oxide;  plant medicinal product;  pyrrolizidine alkaloid;  rinderine n' oxide;  rosmarinic acid;  unclassified drug, Article;  Boraginaceae;  carbon nuclear magnetic resonance;  comparative study;  controlled study;  Cynoglossum columnae;  drug isolation;  electrospray mass spectrometry;  heteronuclear multiple bond correlation;  heteronuclear multiple quantum coherence;  mass spectrometry;  nonhuman;  nuclear Overhauser effect;  plant root;  priority journal;  proton nuclear magnetic resonance;  tandem mass spectrometry;  thin layer chromatography
TODO - Seven secondary metabolites were isolated from the methanolic extracts of the roots and the aerial part of Cynoglossum columnae Ten. β-Arbutin and three pyrrolizidine alkaloids, namely 2′-epi-heliosupine N-oxide, rinderine N-oxide and 3′-O-acetylrinderine N-oxide were isolated from the aerial part of the plant. Echinatine N-oxide, rosmarinic acid and 9″-methyl lithospermate were isolated from the root extract. © 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
ER -