TY - JOUR TI - The role of coffee consumption on the 10-year (2004-2014) Acute Coronary Syndrome (ACS) incidence among cardiac patients: The GREECS observational study AU - Notara, V. AU - Panagiotakos, D.B. AU - Kouvari, M. AU - Tzanoglou, D. AU - Kouli, G. AU - Mantas, Y. AU - Kogias, Y. AU - Stravopodis, P. AU - Papanagnou, G. AU - Zombolos, S. AU - Babatsikou, F. AU - Koutis, C. AU - Pitsavos, C. JO - International Journal of Food Sciences and Nutrition PY - 2015 VL - 66 TODO - 6 SP - 722-728 PB - Taylor and Francis Ltd. SN - 0963-7486, 1465-3478 TODO - 10.3109/09637486.2015.1077795 TODO - coffee, acute coronary syndrome; adverse effects; aged; coffee; complication; female; human; hypertension; incidence; male; middle aged; odds ratio; risk factor; statistical model; very elderly, Acute Coronary Syndrome; Aged; Aged, 80 and over; Coffee; Female; Humans; Hypertension; Incidence; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors TODO - The association between long-term coffee consumption and 10-year cardiovascular disease incidence among Acute Coronary Syndrome (ACS) patients was evaluated. From 2003 to 2004, 2172 ACS consecutive patients from six major Greek hospitals were enrolled. During 2013-2014, the 10-year follow-up was performed (88% participation rate) and recurrent fatal or nonfatal ACS was recorded. Baseline coffee consumption (cups/day) was assessed using a semiquantitative Food Frequency Questionnaire. Multi adjusted analysis revealed that 1-2 cups of coffee/day versus no consumption had an adverse effect on the ACS incidence [odds ratio (OR) = 1.35, 95% confidence interval (CI) 1.01, 1.79]. In subgroup analysis, with hypertension as strata, only the normotensive reached significance. Odds ratios for 1-2 and ≥3 cups relative to no consumption were [OR = 1.66, 95% CI 1.07, 2.60] and [OR = 1.86, 95% CI 1.06, 3.27], respectively, after controlling for potential confounders. Thus, avoidance of coffee may be of high importance to ameliorate disease prognosis among cardiac patients. © 2015 Taylor & Francis. ER -