TY - JOUR TI - Remedies of animal origin and their indications in Nikolaos Myrepsos׳ Dynameron AU - Valiakos, E. AU - Marselos, M. AU - Grafakou, M.E. AU - Skaltsa, H. AU - Sakellaridis, N. JO - Journal of Ethnopharmacology PY - 2021 VL - 276 TODO - null SP - null PB - Elsevier Ireland Ltd SN - 0378-8741 TODO - 10.1016/j.jep.2021.114191 TODO - abdomen; animal product; arthritis; Article; cardiovascular disease; cardiovascular system; dynameron; ear disease; eye disease; gastrointestinal disease; gout; gynecologic disease; healing; honey; human; lung disease; medical literature; medical practice; medical terminology; milk; mouth cavity; nervous system; nonhuman; respiratory tract disease; skin disease; urogenital tract disease; animal; factual database; Middle East; traditional medicine, biological product; materia medica; tissue extract, Animals; Biological Products; Byzantium; Databases, Factual; Honey; Humans; Materia Medica; Medicine, Traditional; Milk; Tissue Extracts TODO - Ethnopharmacological relevance: Dynameron is a Byzantine medical compendium, divided into 24 sections, in accordance with the letters of the Greek alphabet. Being the largest medical and pharmaceutical book ever written in Byzantium, Dynameron contains 2667 recipes intended to treat many pathological conditions. A lot of information convey to us through prescriptions. In addition to plants, Nikolaos Myrepsos proposes the use of many animals, animal parts and animal by-products, for the treatment of various diseases. This article presents for the first time a full account of the animal products included in Dynameron. Aim of the study: In continuation to our previous studies, this paper focuses on the use of animal products in composite medicines described in Dynameron. An effort was made to trace down the use of similar or identical animal products in texts of earlier medical writers. Recording recipes with animals or animal products intended for use in everyday medical practice highlights the timeless belief in their healing properties. Materials and methods: Our main source of material is the recent digital edition of Nikolaos Myrepsos’ Dynameron. This huge treatise was written in the 13th century and reflects in many ways the long medical tradition of the Greek, the Hellenistic and the Roman eras, having also received influences from the materia medica of Arabic medicine. In addition, information from dictionaries and databases were cross-checked to confirm and classify the animals and their products and to identify them. For the various pathological conditions these products are meant for, we have used the current medical terminology. Results: In the present study, we could identify the therapeutic use of 93 animals. In several instances, Myrepsos suggests the use of specific organs of an animal, and for that reason he includes in his treatise 16 anatomical parts of different animals. Moreover, Dynameron comprises also 34 animal by-products, such as milk and honey. Medicines of animal origin are used in recipes concerning diseases of the respiratory, the digestive, the cardiovascular and the urinary system, as well as gynecological diseases, and ailments of the eyes, the ears and the skin. Conclusions: Of the 2667 recipes of Dynameron, 344 recipes contain medicines of animal origin, which can be detected in totally 769 citations. In addition, 626 citations for animal by-products are found in 268 recipes. Honey and milk are quoted in 2136 recipes, mostly as excipients. Dietary instructions are present on many occasions, reflecting the attitude for a healthy everyday life, similar to the modern beliefs pertaining to food as an essential factor for a good health. © 2021 Elsevier B.V. ER -