TY - JOUR
TI - Nuchal-type fibroma: Single-center experience and systematic literature review
AU - Kostakis, I.D.
AU - Feretis, T.
AU - Damaskos, C.
AU - Garmpis, N.
AU - Liapis, G.
AU - Pateras, I.
AU - Garmpi, A.
AU - Georgakopoulou, V.E.
AU - Antoniou, E.A.
JO - In vivo (Athens, Greece)
PY - 2020
VL - 34
TODO - 5
SP - 2217-2223
PB - International Institute of Anticancer Research
SN - null
TODO - 10.21873/invivo.12032
TODO - adult;  Article;  case report;  clinical article;  contrast enhancement;  data base;  excision;  female;  fibroma;  histopathology;  human;  human cell;  immunohistochemistry;  male;  middle aged;  muscle;  nape;  nuclear magnetic resonance imaging;  splenius muscle;  systematic review;  trapezius muscle;  tumor volume;  young adult;  differential diagnosis;  Gardner syndrome;  genetics;  head and neck tumor;  neck;  tumor recurrence, Adult;  Diagnosis, Differential;  Female;  Fibroma;  Gardner Syndrome;  Head and Neck Neoplasms;  Humans;  Male;  Middle Aged;  Neck;  Neoplasm Recurrence, Local;  Young Adult
TODO - Background: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue. Our aim was to present our experience via two cases of this tumor and a comprehensive review of the literature. Patients and Methods: We report a case of a 23-year-old female with a mass located in the posterior neck and the upper back and a case of a 50-year-old male with a mass located in the posterior neck, which were proved to be nuchal-type fibromas in the histopathological examination. We also searched the PubMed/Medline database for published cases of nuchal-type fibromas. Results and Discussion: Nuchaltype fibroma is a rare benign tumor arising from the connective tissue, usually in the posterior neck, which affects different ages, with most patients being male. It is a poorly circumscribed tumor consisting of hypocellular, thick, dense and haphazardly arranged collagen bundles with entrapped adipocytes, nerve fibers and muscle fascicles and a few scattered spindle cells, which are CD34 positive. Its excision is curative, and the recurrence risk is generally low. However, patients with Gardner's syndrome may experience recurrence more frequently. Conclusion: Nuchal-type fibroma should be included in the differential diagnosis of subcutaneous, soft-tissue masses, especially when these involve the posterior neck. © 2020 International Institute of Anticancer Research. All rights reserved.
ER -