TY - JOUR
TI - Review of the literature on leiomyoma and leiomyosarcoma of the adrenal gland: A systematic analysis of case reports
AU - SAKELLARIOU, M.
AU - DELLAPORTAS, D.
AU - PEPPA, M.
AU - SCHIZAS, D.
AU - PIKOULIS, E.
AU - NASTOS, K.
JO - In vivo (Athens, Greece)
PY - 2020
VL - 34
TODO - 5
SP - 2233-2248
PB - International Institute of Anticancer Research
SN - null
TODO - 10.21873/invivo.12034
TODO - adrenal gland;  anorexia;  bilateral cancer;  comorbidity;  Epstein Barr virus infection;  fever;  flank pain;  follow up;  histology;  human;  leiomyoma;  leiomyosarcoma;  malaise;  muscle tumor;  Review;  risk factor;  smooth muscle cell;  systematic review;  adrenal gland;  adrenal tumor;  case report;  leiomyosarcoma;  prognosis, Adrenal Gland Neoplasms;  Adrenal Glands;  Humans;  Leiomyoma;  Leiomyosarcoma;  Prognosis
TODO - Background/Aim: To date few cases of smooth muscle-derived tumors of the adrenal gland have been reported and their treatment remains a medical challenge. The aim of this manuscript was to systematically review the literature and present the tumor characteristics and their management in order to provide a standardized approach to their diagnosis and management. Materials and Methods: We searched five databases (PubMed, Scopus, Elsevier, ResearchGate, Google scholar) for relevant articles published until March 2020. Results: Twenty-two cases of adrenal leiomyoma, four cases of adrenal smooth muscle tumor and forty-five cases of adrenal leiomyosarcoma were included. Conclusion: We present the demographic, clinical, radiological, pathological and oncological characteristics and prognosis of tumors of the adrenal gland arising from smooth muscle cells, as well as describe the common clinical investigations and therapeutic modalities that have been reported as part of their management. © 2020 International Institute of Anticancer Research. All rights reserved.
ER -