TY - JOUR TI - Comparison of MIC test strip and sensititre YeastOne with the CLSI and EUCAST broth microdilution reference methods for in vitro antifungal susceptibility testing of Cryptococcus neoformans AU - Delma, F.Z. AU - Al-Hatmi, A.M.S. AU - Buil, J.B. AU - Van Der Lee, H. AU - Tehupeiory-Kooreman, M. AU - Sybren De Hoog, G. AU - Meletiadis, J. AU - Verweij, P.E. JO - Antimicrobial Agents and Chemotherapy PY - 2020 VL - 64 TODO - 4 SP - null PB - American Society for Microbiology SN - 0066-4804, 1098-6596 TODO - 10.1128/AAC.02261-19 TODO - amphotericin B; fluconazole; flucytosine; isavuconazole; voriconazole; antifungal agent, antifungal susceptibility; Article; broth dilution; Cryptococcus neoformans; device comparison; fungus isolation; in vitro study; minimum inhibitory concentration; nonhuman; priority journal; comparative study; cryptococcosis; Cryptococcus neoformans; drug effect; human; isolation and purification; microbial sensitivity test; microbiology; procedures; time factor, Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Humans; Microbial Sensitivity Tests; Time Factors TODO - We compared MIC test strip (MTS) and Sensititre YeastOne (SYO) methods with EUCAST and CLSI methods for amphotericin B, 5-fluocytosine, fluconazole, voriconazole, and isavuconazole against 106 Cryptococcus neoformans isolates. The overall essential agreement between the EUCAST and CLSI methods was >72% and >94% at ±1 and ±2 dilutions, respectively. The essential agreements between SYO and EUCAST/CLSI for amphotericin B, 5-flucytosine, fluconazole, and voriconazole were >89/>93% and between MTS and EUCAST/CLSI were >57/>75%. Very major error rates were low for amphotericin B and fluconazole (<3%) and a bit higher for the other drugs (<8%). Copyright © 2020 American Society for Microbiology. All Rights Reserved. ER -