TY - JOUR TI - Synthesis, characterization and evaluation of aqueous Zn-based quantum dots for bioapplications AU - Papadopoulou, A. AU - Chalmpes, N. AU - Gournis, D. AU - Kostopoulou, N. AU - Efthimiadou, E.K. JO - Dalton Transactions PY - 2022 VL - 51 TODO - 9 SP - 3452-3461 PB - Royal Society of Chemistry SN - 1477-9226, 1364-5447 TODO - 10.1039/d1dt04021a TODO - null TODO - Semiconducting nanoparticles called quantum dots (Qds) present unique optoelectronic properties based on their extremely small size, composition, and spherical shape, which make them suitable for use as diagnostic and theranostic agents in biological samples. The main scope of the fabrication of Qds is real-time diagnosis, therapy, drug delivery, and in vitro and in vivo tracking, presenting strong resistance to photobleaching. In this work, quantum dots such as ZnO, ZnSe, ZnS, and doped ZnS : Mn and ZnS : Cd were developed via a simple sol-gel synthesis in an aqueous solution. Morphological, structural, and optical characterizations were investigated. Moreover, an in vitro biological evaluation of Qds was performed. The results indicate that the photoluminescence is enhanced after doping ZnS Qds with Mn2+ and Cd2+. Qds have been synthesized for use as fluorescent agents for real-time monitoring in bio-applications. © 2022 The Royal Society of Chemistry. ER -