TY - JOUR
TI - Vagiallene, a Rearranged C 15 Acetogenin from Laurencia obtusa
AU - Perdikaris, S.
AU - Mangoni, A.
AU - Grauso, L.
AU - Papazafiri, P.
AU - Roussis, V.
AU - Ioannou, E.
JO - Organic Letters
PY - 2019
VL - 21
TODO - 9
SP - 3183-3186
PB - American Chemical Society
SN - 1523-7060, 1523-7052
TODO - 10.1021/acs.orglett.9b00897
TODO - acetogenin;  antineoplastic agent;  plant extract, cell survival;  chemical structure;  chemistry;  conformation;  drug effect;  human;  isolation and purification;  isomerism;  Laurencia;  molecular dynamics;  quantum theory;  thermodynamics;  tumor cell line, Acetogenins;  Antineoplastic Agents;  Cell Line, Tumor;  Cell Survival;  Humans;  Isomerism;  Laurencia;  Molecular Conformation;  Molecular Dynamics Simulation;  Molecular Structure;  Plant Extracts;  Quantum Theory;  Thermodynamics
TODO - Vagiallene (1), a rearranged C 15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent from the organic extract of the red alga Laurencia obtusa from Lefkada island. The planar structure and the relative configuration of 1 were established on the basis of extensive analysis of its spectroscopic data, while its absolute configuration was determined by comparison of its experimental and quantum-mechanically predicted electronic circular dichroism spectra. © 2019 American Chemical Society.
ER -