TY - JOUR
TI - Off Label Use of Teriparatide in Spine
AU - Drakopoulos, Panagiotis
AU - Flevas, Dimitrios A.
AU - Galanopoulos,
AU - Ioannis P.
AU - Lepetsos, Panagiotis
AU - Zafeiris, Christos
JO - CUREUS
PY - 2021
VL - 13
TODO - 7
SP - null
PB - CUREUS INC
SN - null
TODO - 10.7759/cureus.16522
TODO - off-label; teriparatide; spine; spinal fusion; parathyroid hormone
TODO - Teriparatide belongs to osteo-anabolic compounds and has been used in
recent years to treat patients with osteoporosis, with the benefits of
increased bone density. Its osteo-anabolic action has led to the
investigation of the use of teriparatide for the improvement of bone
quality. Apart from the enhancement of fracture union, teriparatide has
been extensively studied in the promotion of fusion rate after spinal
fusion. This study summarizes the preclinical and clinical results of
the off-label use of teriparatide in the spine, and specifically its
intermittent administration after instrumented spinal arthrodesis along
with its impact on the spinal bone quality and spinal bone mineral
density.
ER -