TY - JOUR
TI - Spirochetal uveitis: Spectrum of clinical manifestations, diagnostic and
therapeutic approach, final outcome and epidemiological data
AU - Kalogeropoulos, Dimitrios
AU - Asproudis, Ioannis
AU - Stefaniotou, Maria
AU - and Moschos, Marilita
AU - Gartzonika, Constantina
AU - Bassukas, Ioannis
AU - and Konitsiotis, Spiros
AU - Milionis, Haralampos
AU - Gaitanis, Georgios
AU - and Malamos, Konstantinos
AU - Kalogeropoulos, Chris
JO - International Ophthalmology
PY - 2021
VL - 41
TODO - 12
SP - 4111-4126
PB - Springer-Verlag
SN - 0165-5701
TODO - 10.1007/s10792-021-01984-x
TODO - Spirochetes; Syphilis; Leptospira; Borrelia; Infectious uveitis
TODO - Purpose Analysis of cases with spirochetal uveitis related to
spirochetes in a tertiary referral academic center.
Methods Retrospective study of patients diagnosed with uveitis
attributed to Treponema pallidum, Leptospira spp. and Borrelia
burgdorferi from June 1991 until December 2019.
Results A total of 57 cases of spirochetal uveitis (22 patients with T.
pallidum, 26 with Leptospira spp., and 9 with B. burgdorferi) that
consisted 1% of the overall number of uveitics were recorded. All these
cases presented with a wide spectrum of clinical presentations (anterior
uveitis, posterior uveitis, panuveitis, vasculitis, papillitis, and in
some rare cases concomitant posterior scleritis). The treatment included
mainly penicillin or doxycycline, while corticosteroids were
administered systematically in some cases with Borrelia or Leptospira
infection. The final visual outcome was favorable (>6/10 in Snellen
visual acuity) in approximately 76% of our patients.
Conclusion Despite being rare, spirochetal uveitis can be detrimental
for the vision and must always be included in the differential
diagnosis.
ER -