TY - JOUR TI - The role of obesity on urinary incontinence and anal incontinence in women: a review AU - Doumouchtsis, S. K. AU - Loganathan, J. AU - Pergialiotis, V JO - BJOG: An International Journal of Obstetrics and Gynaecology PY - 2022 VL - 129 TODO - 1 SP - 162-170 PB - Wiley SN - 1470-0328, 1471-0528 TODO - 10.1111/1471-0528.16848 TODO - Anal incontinence; obesity; pelvic floor; urinary incontinence; women TODO - Obesity prevalence is increasing worldwide, with significant healthcare implications. We searched PubMed/MEDLINE, Embase and the Cochrane Library for articles registered until June 2020 to explore the relationship between obesity and urinary (UI) and anal incontinence (AI). Obesity is associated with low-grade, systemic inflammation and proinflammatory cytokine release, producing reactive oxygen species and oxidative stress. This alters collagen metabolism and, in combination with increased intra-abdominal pressure, contributes to the development of UI. Whereas in AI, stool consistency may be a factor. Weight loss can reduce UI and should be a management focus; however, the effect of weight loss on AI is less clear. ER -