TY - JOUR TI - Simultaneous Bilateral Spontaneous Pneumothorax in an Adult Patient With Pulmonary Langerhans Cell Histiocytosis: A Case Report AU - Karamouzos, V. AU - Prokakis, C. AU - Kosmopoulou, F. AU - Karanikolas, E. AU - Kalogeropoulou, C. AU - Aretha, D. AU - Panagiotopoulos, N. AU - Koletsis, E. AU - Velissaris, D. JO - Journal of Investigative Medicine High Impact Case Reports PY - 2018 VL - 6 TODO - null SP - null PB - SAGE Publications Ltd SN - 2324-7096 TODO - 10.1177/2324709618792945 TODO - levothyroxine; paracetamol; ranitidine; sultamicillin, abrasion; adult; anemia; Article; atelectasis; breathing rate; bronchoscopy; case report; clinical article; computer assisted tomography; cytology; dyspnea; emergency ward; female; hospitalization; human; human tissue; hypoxemia; immunohistochemistry; Langerhans cell histiocytosis; leukocytosis; lung alveolus cell; lung auscultation; lung cyst; lung surgery; mechanical abrasion; pleurodesis; priority journal; purpura; respiratory distress; smoking cessation; spontaneous pneumothorax; subcutaneous emphysema; tachypnea; thoracoscopic bullectomy; thoracoscopy; thorax pain; thorax radiography; young adult TODO - We report a case of a young female with known history of pulmonary Langerhans cell histiocytosis who was initially presented in the emergency department of a university hospital with respiratory distress. Clinical assessment and diagnostic workup revealed left hemithorax subcutaneous emphysema, bilateral pneumothorax, and atelectasis in both lower lung lobes. The patient was treated with bilateral staged thoracoscopic bullectomy and mechanical abrasion of the parietal pleura combined with chemical pleurodesis with talc. A new occurrence of right-sided pneumothorax was noticed 3 days after surgery, which was treated with chest tube insertion and chemical pleurodesis. The aforementioned surgical approach resulted in complete lung expansion and the patient’s full recovery. A review of pulmonary Langerhans cell histiocytosis and treatment options in cases of pneumothorax due to lung histiocytosis is also presented in this report. © 2018 American Federation for Medical Research. ER -