TY - JOUR
TI - HLA ANTIGENS AND BRONCHOGENIC-CARCINOMA IN THE GREEK POPULATION
AU - TOUMBIS, M
AU - ZERVAS, J
AU - ANAGNOSTOPOULOU, O
AU - KONSTANTOPOULOS, K
AU - and KRIMBENI, G
AU - KOTSOVOULOU, V
AU - FESSAS, F
JO - Acta Oncologica
PY - 1991
VL - 30
TODO - 5
SP - 575-578
PB - Universitetsforlaget (Scandinavian University Press)
SN - 0284-186X, 1651-226X
TODO - 10.3109/02841869109092420
TODO - HLA-ANTIGENS; BRONCHOGENIC CARCINOMA
TODO - The distribution of HLA antigens was studied in 85 Greek patients with
bronchogenic carcinoma. Fifty-seven specific HLA antisera were used to
determine 27 HLA-A and B antigens, with the two-stage standard NIH
microlymphocytotoxicity assay. The results were compared with those in a
control group, consisting of 400 healthy individuals. In the whole group
of patients there was a significantly higher frequency of HLA-AW19 and
HLA-A29 (p < 0.003 and p < 0.006 respectively) and a lower frequency of
HLA-A2 and HLA-A3 (p < 0.014 and p < 0.006 respectively) than in the
control population. In patients with squamous cell carcinoma there was a
significantly higher frequency of HLA-AW19 and lower frequency of HLA-A2
(p < 0.02 and p < 0.05 respectively). In small cell carcinoma patients
there was a significantly lower frequency of HLA-A3 (p < 0.04) than
among the controls. In patients with adenocarcinoma no significant
change of HLA antigen frequencies was observed when compared to the
controls.
ER -