TY - JOUR
TI - LABOR CHARACTERISTICS OF UNCOMPLICATED PROLONGED PREGNANCIES AFTER
INDUCTION WITH INTRACERVICAL PROSTAGLANDIN-E2 GEL VERSUS INTRAVENOUS
OXYTOCIN
AU - PAPAGEORGIOU, I
AU - TSIONOU, C
AU - MINARETZIS, D
AU - MICHALAS, S and
AU - ARAVANTINOS, D
JO - Gynecologic and Obstetric Investigation
PY - 1992
VL - 34
TODO - 2
SP - 92-96
PB - Karger
SN - 0378-7346, 1423-002X
TODO - 10.1159/000292734
TODO - LABOR INDUCTION; PROSTAGLANDIN E2; OXYTOCIN; UNRIPE CERVIX
TODO - Labor characteristics after intracervical application of 0.5 mg
prostaglandin (PG) E2 gel (n = 83)versus intravenous administration of
oxytocin (n = 82) for labor induction were investigated in uncomplicated
prolonged pregnancies with unripe cervix. The induction to delivery time
as well as the total oxytocin dose were significantly reduced in the
PGE2 group (p < 0.001). Cesarean sections, instrumental deliveries and
fetal distress had the same frequency, but the failures of trial were
significantly higher in the oxytocin group than in the PGE, group (20.7
vs. 6%, p < 0.01). Twenty-four percent of women needed a second PGE2
dose, and almost half of the women in the PGE2 group experienced
‘spontaneous’ labor. More neonates in the oxytocin group had 5-min Apgar
scores < 7 (p < 0.05). Intracervical PGE2 gel application is superior to
intravenous oxytocin in terms of shortening the induction-delivery
interval and increasing the frequency of successful vaginal delivery. In
addition, it is safe for mother and fetus.
ER -