TY - JOUR
TI - POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS AND MULTIPLE-SCLEROSIS
AU - PODIKOGLOU, DG
AU - LIANOU, PE
AU - TSAKANIKAS, CD
AU - PAPAVASSILIOU, JT
JO - Functional Neurology
PY - 1994
VL - 44
TODO - 1
SP - 129-132
PB - LITTLE BROWN CO
SN - null
TODO - 10.1212/WNL.44.1.129
TODO - null
TODO - We tested peripheral blood from 60 patients with definite multiple
sclerosis (MS) and 60 healthy controls for polymorphonuclear leukocyte
(PMNL) functions and found significant disorders in adherence (9.07%
+/- 8.18% far patients versus 28.97% +/- 5.76% for controls),
chemotaxis (18.32 +/- 3.1 for patients versus 30.49 +/- 4.52 for
controls), phagocytosis (73.6 +/- 25.25 for patients versus 111.2 +/-
25.7 for controls), and bactericidal action (10.35% +/- 5% for
patients versus 25.09% +/- 4.82% for controls). All differences were
significant (p < 0.001). We confirmed the results by retesting 3 to 8
months later. The depressed PMNL functions in MS patients may explain
their increased susceptibility to infections of the respiratory,
digestive, and urinary tracts.
ER -