TY - JOUR
TI - THE PROGNOSTIC IMPORTANCE OF DELUSIONS IN DEPRESSION - A 6-YEAR
PROSPECTIVE FOLLOW-UP-STUDY
AU - LYKOURAS, L
AU - CHRISTODOULOU, GN
AU - MALLIARAS, D
AU - STEFANIS, C
JO - Journal of Affective Disorders
PY - 1994
VL - 32
TODO - 4
SP - 233-238
PB - ELSEVIER SCIENCE BV
SN - 0165-0327
TODO - 10.1016/0165-0327(94)90086-8
TODO - DELUSION; DEPRESSION; FOLLOW-UP; PSYCHOPROPHYLAXIS
TODO - The authors followed 32 delusional and 41 unipolar non-delusional
depressed patients 6 years after hospital discharge. Long-term outcome,
as determined by the frequency of the relapses, number of
hospitalizations, chronic course of illness as well as clinical status
and global functioning at the end of the 6-year period, failed to
differentiate the two patient groups. Discontinuation of maintenance
medication in both groups or of antipsychotics in the delusional group
was associated with a high rate of relapses. Our findings indicate that
delusional depression has a similar clinical course to that of
non-delusional depression, underline the importance of
psychoprophylactic treatment and question the efficacy of monotherapy
with antidepressants in the prevention of relapses of delusional
depression.
ER -