TY - JOUR TI - CYTOGENETIC STUDY OF 11 GASTRIC ADENOCARCINOMAS AU - PANANI, AD AU - FERTI, A AU - MALLIAROS, S AU - RAPTIS, S JO - CANCER GENETICS AND CYTOGENETICS PY - 1995 VL - 81 TODO - 2 SP - 169-172 PB - Elsevier Science Publ Co Inc, New York SN - 0165-4608 TODO - 10.1016/0165-4608(94)00230-9 TODO - null TODO - We describe the cytogenetic findings in 11 gastric cancer cases. Nine cases showed a variable number of numerical and structural aberrations, while two cases had a normal karyotype. The chromosomes most frequently involved are chromosome 3 in six cases, 6 in four cases, and 13 in three cases. They mainly exhibited structural aberrations. An additional segment on chromosome 3p was observed in three cases, while two cases had a del(3q). A der(5) chromosome resulting from a translocation between chromosomes 3 and 5 was observed in two cases. Both cases had also a del(6q), a der(la), and an add(17p) chromosome as common abnormalities. Deletion of 6q chromosome distal to band 6q21 was observed in three cases. Trisomy 8 as a sole anomaly was found in one case. Our cytogenetic findings are discussed in relation to the reported in the literature data. ER -