TY - JOUR TI - DETECTION OF HUMAN PAPILLOMAVIRUS DNA IN NONGENITAL SEBORRHEIC KERATOSES AU - TSAMBAOS, D AU - MONASTIRLI, A AU - KAPRANOS, N AU - GEORGIOU, S and AU - PASMATZI, E AU - STRATIGOS, A AU - KOUTSELINI, H AU - BERGER, H JO - Archives of Dermatological Research. Archiv fόr Dermatologische Forschung PY - 1995 VL - 287 TODO - 6 SP - 612-615 PB - Springer-Verlag SN - 0340-3696, 1432-069X TODO - 10.1007/BF00374085 TODO - HYBRIDIZATION TECHNIQUE IN SITU; PAPILLOMAVIRUS; SEBORRHEIC KERATOSIS TODO - The histological similarities of seborrhoeic keratoses and common warts led to the investigation of the possible occurrence of human papillomavirus DNA (HPV-DNA) in a large number of nongenital seborrhoeic keratoses using the in situ hybridization technique, All specimens derived from normal skin (n = 173) were negative for the applied HPV-DNA probe, whereas the HPV genome was detected in 33 of 173 seborrhoeic keratosis specimens (19.65%). Of 34 HPV-positive specimens, 15 contained types 6/11 and 14 types 31/33/35, and 5 showed no positive reaction to the applied types. These results suggest that a considerable percentage of nongenital seborrhoeic keratoses may be related to an HPV infection. ER -