TY - JOUR
TI - A triclinic crystal form of the lectin concanavalin A
AU - Kanellopoulos, PN
AU - Tucker, PA
AU - Pavlou, K
AU - Agianian, B and
AU - Hamodrakas, SJ
JO - Journal of Structural Biology
PY - 1996
VL - 117
TODO - 1
SP - 16-23
PB - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN - 1047-8477, 1095-8657
TODO - 10.1006/jsbi.1996.0065
TODO - null
TODO - The molecular structure of a triclinic crystal form of concanavalin A
has been refined at 2.4 Angstrom resolution. The crystals have unit cell
dimensions a 78.8 Angstrom, b = 79.3 Angstrom, c = 133.3 Angstrom, alpha
= 97.1 degrees, beta = 90.2 degrees, and gamma = 97.5 degrees and
contain two tetramers per asymmetric unit each with approximate 222
symmetry. The final crystallographic R-factor is 0.205 and the
free-R-factor is 0.265 in the resolution range 6.0 to 2.4 Angstrom The
conformation of the tetramer is more similar to that found in
concanavalin A saccharide complexes than in the previously reported I222
crystal form of uncomplexed concanavalin A. A comparison of the
molecular packing between the two crystal forms shows a more open
arrangement with large solvent channels through the crystal. (C) 1996
Academic Press, Inc.
ER -