TY - JOUR
TI - Pregnancy results after ovum donation following one to seven embryo
transfers
AU - Mantzavinos, T
AU - Rizos, D
AU - Dimitriadou, F
AU - Arvaniti, K and
AU - Kanakas, N
AU - Voutsina, K
JO - Fertility and Sterility
PY - 1996
VL - 66
TODO - 5
SP - 765-768
PB - AMER SOC REPRODUCTIVE MEDICINE
SN - 0015-0282, 1556-5653
TODO - 10.1016/S0015-0282(16)58633-6
TODO - oocyte donation; repeated embryo transfers; embryo quality; endometrial
lining
TODO - Objective: To determine whether failure to achieve pregnancy after
repeated ET after ovum donation was due to an endometrial defect or to
the embryo quality.
Design: Retrospective data analysis.
Setting: A private infertility center.
Patient(s): Four hundred sixty-seven donors (513 cycles) undergoing IVF
donating oocytes to 266 recipients (423 cycles).
Intervention(s): Hormonal endometrial preparation with increasing
dosages of valerate E(2) (2, 4, and 6 mg) and 100 mg of P.
Main Outcome Measure(s): Pregnancy rates (PRs) and abortion rates in
patients undergoing one to seven ETs after ovum donation.
Result(s): Pregnancy rates in recipients that had one or two ETs were
significantly higher (34.8%) compared with those of recipients having
three or more ETs (15.1%). Abortion rates were significantly higher
(54.5%) in recipients repeating more than three ETs than in the
recipients having one or two ETs (29.1%).
Conclusion(s): Recipients that had failed to establish a pregnancy after
two ETs had a lower PR in successive attempts, possibly because of a
defect of their endometrial lining.
ER -