TY - JOUR
TI - Preliminary evaluation of the potential prognostic value of serum levels
of immunoglobulins (IgA, IgM, IgG, IgE) in patients with gastric cancer
AU - Tsavaris, N
AU - Tsigalacis, D
AU - Kosmas, C
AU - Koufos, C and
AU - Vaiopoulos, G
AU - Tzivras, M
AU - Kouraklis, G
AU - Papadimas, V and
AU - Georgoulis, V
AU - Archimandritis, A
AU - Sechas, M
JO - International Journal of Biological Markers
PY - 1998
VL - 13
TODO - 2
SP - 87-91
PB - Wichtig Editore
SN - 0393-6155, 1724-6008
TODO - 10.1177/172460089801300204
TODO - gastric cancer; immunoglobulins; prognosis survival
TODO - Sixty patients with advanced gastric carcinoma who refused to receive
cytotoxic chemotherapy were examined for serum immunoglobulin levels
(Igc, IgM, IgA, IgE). Three samples were obtained every two months
thereafter The group of patients who had above-normal values of one or
more of the examined immunoglobulins had a longer survival than the
other (p<0.024). Immunoglobulin values were independent of the
Helicobacter pylori antibody titer and of acute phase reactants. it is
concluded that survival potentially correlates with serum immunoglobulin
levels. Further studies including larger numbers of patients and
correlating serum immunoglobulin levels with specific clinical
parameters are needed to establish the prognostic role of serum
immunoglobulins in patients with gastric carcinoma.
ER -