TY - JOUR TI - Exercise-induced ST-segment changes in lead V-1 identify the significantly narrowed coronary artery in patients with single-vessel disease - Correlation with thallium-201 scintigraphy and coronary arteriography data AU - Michaelides, AP AU - Psomadaki, ZD AU - Richter, DJ AU - Dilaveris, PE and AU - Andrikopoulos, GK AU - Kakaidis, S AU - Stefanadis, C AU - Gialafos, JE and AU - Toutouzas, PK JO - Journal of Electrocardiology PY - 1999 VL - 32 TODO - 1 SP - 7-14 PB - CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS SN - 0022-0736, 1532-8430 TODO - 10.1016/S0022-0736(99)90016-X TODO - exercise testing; ST-segment changes; lead V-1; coronary; artery disease TODO - We investigated the correlation of exercise-induced ST-segment changes in lead V-1, with the detection of the significantly narrowed vessel that induced ischemia during exercise in myocardial areas supplied by this vessel. We studied 198 patients who underwent exercise testing, thallium-201 scintigraphy, and coronary arteriography. The patients were divided into three groups. In group 1 (ST-segment elevation in lead V-1), 84% had left anterior descending coronary artery disease (P < .001); in group 2 (ST-segment depression in lead V-1), 76% had right coronary artery disease (P < .001); and in group 3 (no ST-segment changes in lead V-1), there were no significant differences concerning the narrowed vessel. Thallium-201 scintigraphy data confirmed the existence of the reversible perfusion defect(s) in an area(s) of myocardium supplied by the respective coronary arteries (P < .001). Exercise-induced ST-segment elevation or depresssion in V-1 may identify the obstructed vessel in patients with single-vessel disease and without prior myocardial infarction. ER -