TY - JOUR
TI - Lactic acid polymers as biodegradable carriers of fluoroquinolones: An
in vitro study
AU - Kanellakopoulou, K
AU - Kolia, M
AU - Anastassiadis, A
AU - Korakis, T and
AU - Giamarellos-Bourboulis, EJ
AU - Andreopoulos, A
AU - Dounis, E and
AU - Giamarellou, H
JO - Antimicrobial Agents and Chemotherapy
PY - 1999
VL - 43
TODO - 3
SP - 714-716
PB - AMER SOC MICROBIOLOGY
SN - 0066-4804, 1098-6596
TODO - 10.1128/AAC.43.3.714
TODO - null
TODO - A biodegradable polymer of DL-dilactide that facilitates release of
ciprofloxacin or pefloxacin at levels exceeding MICs for the causative
microorganisms of chronic osteomyelitis is described. Duration and peak
of release were found to depend on the molecular weight of the polymer.
Its characteristics make it promising for treating chronic bone
infections.
ER -