TY - JOUR
TI - Short-term associations between fine and coarse particulate matter and hospitalizations in Southern Europe: Results from the MED-PARTICLES project
AU - Stafoggia, M.
AU - Samoli, E.
AU - Alessandrini, E.
AU - Cadum, E.
AU - Ostro, B.
AU - Berti, G.
AU - Faustini, A.
AU - Jacquemin, B.
AU - Linares, C.
AU - Pascal, M.
AU - Randi, G.
AU - Ranzi, A.
AU - Stivanello, E.
AU - Forastiere, F.
AU - Angelini, P.
AU - Bisanti, L.
AU - Catrambone, M.
AU - Chiusolo, M.
AU - Davoli, M.
AU - de’ Donato, F.
AU - Demaria, M.
AU - Gandini, M.
AU - Grosa, M.
AU - Ferrari, S.
AU - Pandolfi, P.
AU - Pelosini, R.
AU - Perrino, C.
AU - Pietrodangelo, A.
AU - Pizzi, L.
AU - Poluzzi, V.
AU - Priod, G.
AU - Rowinski, M.
AU - Scarinzi, C.
AU - Zauli-Sajani, S.
AU - Dimakopoulou, K.
AU - Elefteriadis, K.
AU - Katsouyanni, K.
AU - Kelessis, A.
AU - Maggos, T.
AU - Michalopoulos, N.
AU - Pateraki, S.
AU - Petrakakis, M.
AU - Rodopoulou, S.
AU - Sypsa, V.
AU - Artiñano, B.
AU - Barrera-Gómez, J.
AU - Basagaña, X.
AU - de la Rosa, J.
AU - Diaz, J.
AU - Karanasiou, A.
AU - Pey, J.
AU - Querol, X.
AU - Sunyer, J.
AU - Tobias, A.
AU - Bidondo, M.
AU - Declercq, C.
AU - Le Tertre, A.
AU - Lozano, P.
AU - Medina, S.
AU - Pascal, L.
AU - MED-PARTICLES Study Group
JO - Environmental Health Perspectives
PY - 2013
VL - 121
TODO - 9
SP - 1026-1033
PB - Public Health Services, US Dept of Health and Human Services
SN - 0091-6765, 1552-9924
TODO - 10.1289/ehp.1206151
TODO - nitrogen dioxide;  ozone;  particulate matter, adolescent;  air pollution;  air quality standard;  air temperature;  airborne particle;  article;  cardiovascular disease;  concentration (parameters);  genetic heterogeneity;  hospitalization;  human;  influenza;  morbidity;  particulate matter;  priority journal;  respiratory tract disease;  season;  sensitivity analysis;  Southern Europe;  time;  analysis;  Cardiovascular Diseases;  city;  Europe;  particle size;  particulate matter;  Poisson distribution;  Respiratory Tract Diseases;  statistics and numerical data;  theoretical model, Cardiovascular Diseases;  Cities;  Europe;  Hospitalization;  Humans;  Models, Theoretical;  Particle Size;  Particulate Matter;  Poisson Distribution;  Respiratory Tract Diseases
TODO - Background: Evidence on the short-term effects of fine and coarse particles on morbidity in Europe is scarce and inconsistent. Objectives: We aimed to estimate the association between daily concentrations of fine and coarse particles with hospitalizations for cardiovascular and respiratory conditions in eight Southern European cities, within the MED-PARTICLES project. Methods: City-specific Poisson models were fitted to estimate associations of daily concentrations of particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5), ≤ 10 (PM10), and their difference (PM2.5-10) with daily counts of emergency hospitalizations for cardiovascular and respiratory diseases. We derived pooled estimates from random-effects meta-analysis and evaluated the robustness of results to co-pollutant exposure adjustment and model specification. Pooled concentration-response curves were estimated using a meta-smoothing approach. Results: We found significant associations between all PM fractions and cardiovascular admissions. Increases of 10 μg/m3 in PM2.5, 6.3 μg/m3 in PM2.5-10, and 14.4 μg/m3 in PM10 (lag 0-1 days) were associated with increases in cardiovascular admissions of 0.51% (95% CI: 0.12, 0.90%), 0.46% (95% CI: 0.10, 0.82%), and 0.53% (95% CI: 0.06, 1.00%), respectively. Stronger associations were estimated for respiratory hospitalizations, ranging from 1.15% (95% CI: 0.21, 2.11%) for PM10 to 1.36% (95% CI: 0.23, 2.49) for PM2.5 (lag 0-5 days). Conclusions: PM2.5 and PM2.5-10 were positively associated with cardiovascular and respiratory admissions in eight Mediterranean cities. Information on the short-term effects of different PM fractions on morbidity in Southern Europe will be useful to inform European policies on air quality standards.
ER -