TY - JOUR
TI - Isolation and structure elucidation of three new dolastanes from the brown alga Dilophus spiralis
AU - Ioannou, E.
AU - Vagias, C.
AU - Roussis, V.
JO - Marine Drugs
PY - 2013
VL - 11
TODO - 4
SP - 1104-1112
PB - MDPI AG
SN - null
TODO - 10.3390/md11041104
TODO - 1,4 dihydroxy 11 oxo 17 dolastene;  1,4 epoxy 17 dolastene;  4 hydroxy 11 oxo 1,17 dolastadiene;  diterpene;  hypoxia inducible factor 1;  unclassified drug, article;  brown alga;  cancer cell;  Dilophus spiralis;  drug cytotoxicity;  drug isolation;  drug structure;  human;  human cell;  infrared spectroscopy;  mass spectrometry;  nuclear magnetic resonance spectroscopy, Dilophus spiralis;  Phaeophyceae
TODO - Three new dolastane diterpenes (1-3) and five previously reported perhydroazulenes were isolated from the organic extracts of the brown alga Dilophus spiralis. The structure elucidation and the assignment of the relative configurations of the isolated natural products were based on extensive analyses of their spectroscopic data, whereas the absolute configuration of metabolite 2 was determined through its chemical conversion to a previously isolated compound of known configuration. © 2013 by the authors; licensee MDPI.
ER -