TY - JOUR
TI - Conformationally constrained adamantaneoxazolines of pharmacological interest
AU - Papanastasiou, I.
AU - Foscolos, G.B.
AU - Tsotinis, A.
AU - Oláh, J.
AU - Ovádi, J.
AU - Radhika Prathalingam, S.
AU - Kelly, J.M.
JO - Heterocycles
PY - 2008
VL - 75
TODO - 8
SP - 2043-2061
PB - 
SN - 0385-5414, 1881-0942
TODO - 10.3987/COM-08-11377
TODO - null
TODO - New conformationally constrained adamantane 2-oxazoline building blocks 1-4 were synthesized and their antimicrotubule and antitrypanosomal potency was investigated. Although most of the new compounds affect tubulin polymerization, this does not make a major contribution to trypanocidal activity. © 2008 The Japan Institute of Heterocyclic Chemistry.
ER -