TY - JOUR
TI - Influence of selenium and Eimeria tenella infection on antioxidant status in chickens
AU - Gabrashanska, M.
AU - Koinarski, V.
AU - Anisimova, M.
AU - Denev, S.
AU - Ermidou-Pollet, S.
JO - Trace Elements and Electrolytes
PY - 2009
VL - 26
TODO - 1
SP - 17-23
PB - Dustri Verlag/Dr. Karl Feistle
SN - 0946-2104
TODO - 10.5414/TEP26017
TODO - alpha tocopherol;  ascorbic acid;  glutathione peroxidase;  malonaldehyde;  retinol;  sel plex;  selenium;  unclassified drug, animal experiment;  animal tissue;  antioxidant activity;  article;  body weight;  chicken;  coccidiosis;  controlled study;  diet supplementation;  Eimeria tenella;  enzyme activity;  nonhuman;  oocyst;  oxidative stress;  priority journal, Eimeria tenella;  Gallus gallus
TODO - The aim of our study was to evaluate the effect of selenium-yeast (Selp-lex 50, Alltech, Inc. Nicholasville, KY, USA) on the antioxidant defense system (vitamin A, C and E, enzyme GPx, Se and MDA), oocyst and lesion index, and body weights in chickens experimentally infected with Eimeria tenella. 100 clinically healthy broiler chickens, Cobb 500 hybrids, were divided into 4 groups. Chickens from the first group were untreated and non-infected (control group). The second group consisted of non-infected chickens having received Sel-plex in the food from the 1st day of hatching to the end of the experiment. The chickens in Groups 3 and 4 were individually infected with 8.104 sporulated oocyst of E. tenella on Day 17 post-hatching. The fodder of chickens in Group 4 was supplemented with Sel-plex like the first group. Sel-plex was added at a level of 0.3 mg/kg diet. Liver and serum samples were collected for biochemical analyses on 7th day post infection (dpi). Body weights were check on 1st and 7th dpi. Ceca of infected chickens were scored for lesions and oocyst index on 7 dpi. During the acute stage of eimeriosis an antioxidant imbalance was developed in the liver of the infected chickens. Hypovitaminoses A, Cand E, reduced Se level and GPx-activity and increased MDA were observed. Sel-plex supplementation increased liver vitamin E, Se level and serum GPx-activity, improved body weights in the control and in the infected chickens but did not influence parasitological status. Diet complementation with Sel-plex could be beneficial for the hosts in the treatment of parasitic diseases correlated with high levels of oxidative stress. © 2009 Dustri-Verlag Dr. K. Feistle.
ER -