TY - JOUR
TI - Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity
AU - Halvatsiotis, P.
AU - Kotanidou, A.
AU - Tzannis, K.
AU - Jahaj, E.
AU - Magira, E.
AU - Theodorakopoulou, M.
AU - Konstandopoulou, G.
AU - Gkeka, E.
AU - Pourzitaki, C.
AU - Kapravelos, N.
AU - Papoti, S.
AU - Sileli, M.
AU - Gogos, C.
AU - Velissaris, D.
AU - Markou, N.
AU - Stefanatou, E.
AU - Vlachogianni, G.
AU - Aimoniotou, E.
AU - Komnos, A.
AU - Zafeiridis, T.
AU - Koulouvaris, P.
AU - Armaganidis, A.
AU - Bamias, A.
AU - Dimopoulos, G.
JO - Diabetes Research and Clinical Practice
PY - 2020
VL - 166
TODO - null
SP - null
PB - Elsevier Ireland Ltd
SN - 0168-8227
TODO - 10.1016/j.diabres.2020.108331
TODO - adult;  aged;  aging;  Article;  clinical feature;  comorbidity;  coronavirus disease 2019;  critical illness;  critically ill patient;  demography;  disease burden;  disease duration;  disease severity;  female;  Greece;  hospital admission;  hospital discharge;  human;  hypertension;  infection risk;  intensive care unit;  length of stay;  major clinical study;  male;  mortality;  non insulin dependent diabetes mellitus;  obesity;  observational study;  retrospective study;  Betacoronavirus;  clinical trial;  complication;  Coronavirus infection;  critical illness;  diabetes mellitus;  hospitalization;  isolation and purification;  middle aged;  mortality;  multicenter study;  obesity;  pandemic;  pathophysiology;  prognosis;  risk factor;  survival rate;  virology;  virus pneumonia, Aged;  Betacoronavirus;  Comorbidity;  Coronavirus Infections;  Critical Illness;  Diabetes Mellitus;  Female;  Greece;  Hospitalization;  Humans;  Male;  Middle Aged;  Obesity;  Pandemics;  Pneumonia, Viral;  Prognosis;  Retrospective Studies;  Risk Factors;  Survival Rate
TODO - Aims: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. Methods: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. Results: The median age of the patients was 65.5 (IQR 56–73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5–11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3–9) vs. 9 (IQR 7–14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. Conclusions: Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece. © 2020 Elsevier B.V.
ER -