TY - JOUR TI - A Comprehensive Multidisciplinary Management Plan Is Effective in Reducing the Prevalence of Overweight and Obesity in Childhood and Adolescence AU - Genitsaridi, S.-M. AU - Giannios, C. AU - Karampatsou, S. AU - Papageorgiou, I. AU - Papadopoulos, G. AU - Farakla, I. AU - Koui, E. AU - Georgiou, A. AU - Romas, S. AU - Terzioglou, E. AU - Papathanasiou, C. AU - Kassari, P. AU - Manios, Y. AU - Charmandari, E. JO - Hormone Research in Paediatrics PY - 2020 VL - 93 TODO - 2 SP - 94-107 PB - S Karger AG SN - 1663-2818 TODO - 10.1159/000507760 TODO - 25 hydroxyvitamin D; alanine aminotransferase; albumin; alkaline phosphatase; androstenedione; apolipoprotein A1; apolipoprotein B; aspartate aminotransferase; C reactive protein; cholesterol; corticotropin; ferritin; follitropin; glucose; glutathione peroxidase; hemoglobin A1c; high density lipoprotein cholesterol; hydrocortisone; insulin; lipoprotein; low density lipoprotein cholesterol; luteinizing hormone; prasterone; prolactin; testosterone; thyroglobulin antibody; thyroid peroxidase antibody; thyrotropin; thyroxine; triacylglycerol, adolescent; adult; Article; body mass; chemiluminescence immunoassay; child; childhood obesity; female; follow up; hip circumference; HOMA index; human; hydrocortisone blood level; major clinical study; male; multidisciplinary team; obesity; physical activity; prevalence; priority journal; prospective study; psychologic assessment; waist circumference; young adult; childhood obesity; disease management; Greece; obesity; preschool child; prevalence, Adolescent; Body Mass Index; Child; Child, Preschool; Disease Management; Female; Greece; Humans; Male; Overweight; Pediatric Obesity; Prevalence TODO - Background: Obesity in childhood and adolescence represents a major health problem of our century. In Greece, 30-35% of children and adolescents are overweight or obese. Objective and Hypotheses: To investigate the effectiveness of a comprehensive multidisciplinary personalized management plan at reducing the prevalence of overweight and obesity in childhood and adolescence. Patients and Methods: One thousand (n = 1,000) children and adolescents aged 2-18 years (mean age ± SD: 10.09 ± 2.86 years; 520 females, 480 males) were studied prospectively. Subjects were classified as obese (n = 579, 57.9%), overweight (n = 295, 29.5%) or having a normal body mass index (BMI) (n = 126, 12.6%) according to the International Obesity Task Force cutoff points. All subjects were evaluated by a multidisciplinary team at frequent intervals, received personalized advice on diet and exercise and were studied prospectively for 1 year. Detailed clinical evaluation and laboratory investigations were performed at the beginning and at the end of the study. Results: At initial evaluation, 57.9% of subjects were obese, 29.5% overweight and 12.6% of normal BMI. Indices of cardiometabolic disease were higher in obese than in overweight and normal-BMI subjects. Following 1 year of multidisciplinary management interventions, the prevalence of obesity decreased by 16.8%, the prevalence of normal BMI increased by 8.2%, and all cardiometabolic indices improved significantly. Conclusions: A personalized multidisciplinary management plan is effective at reducing the prevalence of obesity in childhood and adolescence. © 2020 S. Karger AG. All rights reserved. ER -