TY - JOUR
TI - Usefulness of the SAGE score to predict elevated values of brachial-ankle pulse wave velocity in Japanese subjects with hypertension
AU - Tomiyama, H.
AU - Vlachopoulos, C.
AU - Xaplanteris, P.
AU - Nakano, H.
AU - Shiina, K.
AU - Ishizu, T.
AU - Kohro, T.
AU - Higashi, Y.
AU - Takase, B.
AU - Suzuki, T.
AU - Yamazaki, T.
AU - Furumoto, T.
AU - Kario, K.
AU - Inoue, T.
AU - Koba, S.
AU - Takemoto, Y.
AU - Hano, T.
AU - Sata, M.
AU - Ishibashi, Y.
AU - Node, K.
AU - Tanaka, A.
AU - Maemura, K.
AU - Ohya, Y.
AU - Furukawa, T.
AU - Ito, H.
AU - Ohkuma, T.
AU - Ninomiya, T.
AU - Chikamori, T.
AU - Yamashina, A.
AU - Ueda, S.-I.
JO - Hypertension Research
PY - 2020
VL - 43
TODO - 11
SP - 1284-1292
PB - Springer Nature BV
SN - 0916-9636, 1348-4214
TODO - 10.1038/s41440-020-0472-7
TODO - cholesterol;  creatinine;  high density lipoprotein cholesterol, adult;  aged;  Article;  atrial fibrillation;  brachial-ankle pulse wave velocity;  Chronic Kidney Disease Epidemiology Collaboration equation;  cohort analysis;  controlled study;  cross-sectional study;  diagnostic test accuracy study;  diastolic blood pressure;  estimated glomerular filtration rate;  female;  glucose blood level;  human;  hypertension;  Japanese (people);  kidney function;  major clinical study;  male;  mathematical parameters;  multicenter study;  observational study;  prospective study;  receiver operating characteristic;  SAGE score;  scoring system;  sensitivity and specificity;  systolic blood pressure;  waveform;  health status indicator;  hypertension;  Japan;  middle aged;  pathophysiology;  pulse wave, Adult;  Aged;  Cross-Sectional Studies;  Female;  Health Status Indicators;  Humans;  Hypertension;  Japan;  Male;  Middle Aged;  Pulse Wave Analysis
TODO - The score based on the office systolic blood pressure, age, fasting blood glucose level, and estimated glomerular filtration rate (SAGE score) has been proposed as a useful marker to identify elevated values of carotid-femoral pulse wave velocity (PWV). The present cross-sectional study was conducted to examine whether the SAGE score is also a useful marker to identify subjects with elevated brachial-ankle PWV values in Japanese subjects with hypertension. We measured the brachial-ankle PWV and calculated the SAGE score in a total of 1019 employees of a Japanese company with hypertension and 817 subjects with hypertension derived from a multicenter study cohort. The analyses in this study were based on data from these two study groups as well as on a composite population of the two (n = 1836). The receiver operating characteristic curve analysis showed that the area under the curve to identify subjects with brachial-ankle PWV values of ≥1800 cm/s was over 0.70 in each of the three study groups. Even after adjustments, a SAGE score ≥7 had a significant odds ratio for identifying subjects with brachial-ankle PWV values ≥1800 cm/s in the 1836 study subjects from the composite occupational and multicenter study cohort (odds ratio = 2.1, 95% confidence interval = 1.4–3.0, P < 0.01). Thus, in Japanese subjects with hypertension, the SAGE score may be a useful marker for identifying subjects with elevated brachial-ankle PWV values. © 2020, The Japanese Society of Hypertension.
ER -