TY - JOUR
TI - Arm morbidity following treatment of breast cancer with total axillary dissection: A multivariated approach
AU - Keramopoulos, A.
AU - Tsionou, C.
AU - Minaretzis, D.
AU - Michalas, S.
AU - Aravantinos, D.
JO - Oncology (Switzerland)
PY - 1993
VL - 50
TODO - 6
SP - 445-449
PB - 
SN - null
TODO - 10.1159/000227227
TODO - adult;  arm disease;  arm edema;  article;  axillary lymph node;  breast cancer;  breast surgery;  female;  human;  joint mobility;  lymph node dissection;  major clinical study;  mastectomy;  morbidity;  multiple regression;  pain;  priority journal;  shoulder, Age Factors;  Arm;  Breast Neoplasms;  Edema;  Female;  Human;  Lymph Node Excision;  Lymphatic Metastasis;  Mastectomy, Modified Radical;  Mastectomy, Segmental;  Middle Age;  Morbidity;  Movement;  Pain;  Radiotherapy;  Regression Analysis;  Shoulder Joint
TODO - In order to clarify the factors that mainly influence arm morbidity following treatment of breast cancer with the full axillary dissection protocol, we evaluated, in a model of multiple regression analysis, parameters such as the type of breast surgery, adjuvant radiotherapy, time of irradiation, age, number of dissected nodes and axillary nodal status. A total of 104 women were studied. Late arm edema was observed in 17% of the patients and was more frequent when (I) irradiation was given immediately after the operation than if it was given 6 months laler(p = 0.009) and (2) the number of removed nodes exceeded 40 (p = 0.037). Upper limb pain was reported by 16% of the patients and was reported more frequently from patients over 60 years of age (p = 0.036). as well as from patients who underwent modified radical mastectomy (p = 0.044) and those in whom 30-40 nodes were dissected (p = 0.025). Shoulder joint mobility was impaired in 17% of the patients, and it was not affected by any of the examined factors. It seems that conservative breast surgery or adjuvant breast radiotherapy 6 months after the operation might reduce independently the likelihood of arm morbidity by 25%. © 1993 S. Karger AG, Basel.
ER -