TY - JOUR
TI - Evaluation of the end-expiratory pressure by multiple linear regression
and Fourier analysis in humans
AU - Amygdalou, A
AU - Psarakis, C
AU - Vassiliou, P
AU - Dalavanga, YA and
AU - Mandragos, C
AU - Constantopoulos, SH
AU - Behrakis, PK
AU - Vassiliou, MP
JO - Respiratory Medicine
PY - 2002
VL - 96
TODO - 7
SP - 499-505
PB - W B SAUNDERS CO LTD
SN - 0954-6111
TODO - 10.1053/rmed.2002.1305
TODO - end-expiratory pressure; Fourier analysis; multiple linear regression;
respiratory mechanics
TODO - This study was designed to compare the end-expiratory pressure (EEP)
during mechanical ventilation (MV) measured dynamically (EEPdyn), by
multiple linear regression (MLR) of the airway pressure (Pao) vs volume
(V) and flow (V’) and after Fourier analysis (FA) of the Pao and V’. Pao
and V were recorded from 32 ICU patients (II without respiratory
disease, 10 COPD, II ARDS) under MV at three levels of PEEPe (0, 5 and
10 hPa). Volume was calculated by numerical integration of V’. Data were
analysed by MLR and FA, while the actual value of EEPdyn was recognised
on the Pao signal at zero V and V EEPdyn, EEPMLR and EEPFA were compared
for all patients, for each group of patients and for every level of
applied PEEPe. Despite the different evaluation of respiratory mechanics
between MLR and FA, the EEP values were always not significantly
different between the three applied methods (P> 0.05). A high degree of
correlation was found between them, taken two at a time (r > 0.99, P <
0.001). Two non-invasive analytical methods for the evaluation of
respiratory mechanics during MV MLR and FA offer a reliable and
clinically useful estimation of EEP during MV (C) 2002 Published by
Elsevier Science Ltd.
ER -