TY - JOUR
TI - Extended-spectrum beta-lactamase types in Klebsiella pneumoniae and
Escherichia coli in two Greek hospitals
AU - Tzelepi, E
AU - Magana, C
AU - Platsouka, E
AU - Sofianou, D
AU - Paniara, O
AU - and Legakis, NJ
AU - Vatopoulos, AC
AU - Tzouvelekis, LS
JO - International Journal of Antimicrobial Agents
PY - 2003
VL - 21
TODO - 3
SP - 285-288
PB - ELSEVIER SCIENCE BV
SN - 0924-8579
TODO - 10.1016/S0924-8579(02)00361-8
TODO - Enterobacteriaceae; ESBL; beta-lactamases; SHV-5; CTX-M; IBC
TODO - Seventy-nine Klebsiella pneumoniae and 124 Escherichia coli clinical
strains, isolated consecutively during August-October 2001 in two Greek
hospitals, were examined for production of extended-spectrum
beta-lactamases (ESBLs). Seventy-one (35%) isolates (46 K pneumoniae
and 25 E. coli) were ESBL-positive by phenotypic methods. Isoelectric
focusing of beta-lactamases and PCR assays for bla genes showed that
SHV-5-type ESBLs were the most frequent (45 isolates, 22%) followed by
CTX-M (24 isolates, 12%) and IBC (three isolates, 1.5%). The latter
two ESBL types may have been established recently in this setting. (C)
2002 Elsevier Science B.V. and the International Society of
Chemotherapy. All rights reserved.
ER -