TY - JOUR
TI - The association between preeclampsia and arterial stiffness
AU - Hausvater, A.
AU - Giannone, T.
AU - Sandoval, Y.-H.G.
AU - Doonan, R.J.
AU - Antonopoulos, C.N.
AU - Matsoukis, I.L.
AU - Petridou, E.T.
AU - Daskalopoulou, S.S.
JO - JOURNAL OF HYPERTENSION
PY - 2012
VL - 30
TODO - 1
SP - 17-33
PB - Lippincott Williams and Wilkins
SN - -
TODO - 10.1097/HJH.0b013e32834e4b0f
TODO - aldosterone;  angiotensin;  angiotensin II;  angiotensin receptor;  renin, arterial stiffness;  augmentation index;  cardiovascular risk;  carotid artery pulse;  Cochrane Library;  comparative study;  diastolic blood pressure;  disease activity;  disease association;  disease severity;  Embase;  endothelial dysfunction;  femoral artery;  human;  hypertension;  maternal hypertension;  Medline;  meta analysis (topic);  oxidative stress;  pathogenesis;  preeclampsia;  pregnancy;  pregnancy outcome;  priority journal;  proteinuria;  pulse wave;  radial artery;  renin angiotensin aldosterone system;  review;  systematic review (topic);  systolic blood pressure;  trophoblast
TODO - A systematic review and meta-analysis was conducted using MEDLINE, EMBASE, and the Cochrane Library to investigate the association between preeclampsia and arterial stiffness. Twenty-three relevant studies were included. A significant increase in all arterial stiffness indices combined was observed in women with preeclampsia vs. women with normotensive pregnancies [standardized mean difference 1.62, 95% confidence interval (CI) 0.73-2.50]; carotid-femoral pulse wave velocity (cfPWV) and augmentation index (AIx) were also significantly increased (weighted mean difference, WMDcfPWV 1.04, 95% CI 0.34-1.74; WMDAIx 15.10, 95% CI 5.08-25.11), whereas carotid-radial PWV (crPWV) increase did not reach significance (WMDcrPWV 0.99, 95% CI-0.07 to 2.05). Significant increases in arterial stiffness measurements were noted in women with preeclampsia compared with those with gestational hypertension. Arterial stiffness measurements may also be useful in predicting preeclampsia and may play a role in the increased risk of future cardiovascular complications seen in women with a history of preeclampsia. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
ER -